cardiotonic


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cardiotonic

 [kahr″de-o-ton´ik]
1. having a tonic effect on the heart.
2. an agent that so acts.

car·di·o·ton·ic

(kar'dē-ō-ton'ik),
Exerting a favorable, so-called tonic effect on the action of the heart; usually intended to indicate increased force of contraction.
[cardio- + G. tonos, tension]

cardiotonic

/car·dio·ton·ic/ (kahr″de-o-ton´ik) having a tonic effect on the heart; an agent that so acts.

cardiotonic

[kär′dē·ōton′ik]
Etymology: Gk, kardia + tonos, tone
1 pertaining to a substance that tends to increase the efficiency of contractions of the heart muscle.
2 a pharmacological agent that increases the force of myocardial contractions. Cardiac glycosides, derived from certain plant alkaloids, exert a tonic effect by altering the transport of electrolytes across the myocardial membrane, causing a decreased efflux of sodium and calcium and a decreased influx of potassium. Digitoxin and digoxin, widely used cardiac glycosides obtained from leaves of a species of foxglove, increase the force of myocardial contractions, extend the refractory period of the atrioventricular node, and, to a lesser degree, affect the sinoatrial node and the heart's conduction system.

cardiotonic

adjective Referring to a tonic effect on the heart noun An agent with said effect–eg, digitalis

car·di·o·ton·ic

(kahr'dē-ō-ton'ik)
Exerting a favorable, so-called tonic effect on the action of the heart; usually intended to indicate increased force of contraction.
[cardio- + G. tonos, tension]

cardiotonic,

adj/n property of a substance that has an invigorating effect on the heart.

cardiotonic

having a tonic effect on the heart; an agent that so acts.
References in periodicals archive ?
Standard test for phytochemical constituents revealed the presence of saponins, alkaloids, sophisticated lactones, triterpenoids, reducing sugars, amino acids, flavonoids, terpenoids, tannins and cardiotonic glycosides but absence of quinine.
Hawthorn extracts are referred to as a cardiotonic because of their ability to increase the heart's muscle tone.
1996, "Terminalia arjuna an Ayurvedic cardiotonic regulates lipid metabolism in hyperlipaemic rats," Phytotherapy Res.
In addition, a cardiotonic steroid, bufalin, has been shown to induce differentiation of human myeloid leukemia-derived cell lines, HL-60, U937 and ML1, and leukemic cells from 4 of 20 AML patients in primary culture [39,40].
Cardiotonic glycosides are compounds present in some groups of plants with marked pharmacological effects on the digestive system as well as the heart.
Ginger lowers blood pressure through blockade of voltage-dependent calcium channels acting as a cardiotonic pump activator in mice, rabbit and dogs.
Voacamine (55) has been shown to have cardiotonic effects and use as a treatment of heart conditions (2,114).
Effects of Levosimendan, a cardiotonic agent targeted to troponin C, on cardiac function and on phosphorylation and Ca2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart.
Whether these actions underlying the cardiotonic properties seen in myocardial cells also play significant roles in nonexcitable tissues is not known.
Twenty-two subjects took cardiological medication (13 calcium blocker, 3 beta blocker, 3 ACE inhibitor, 2 alpha blocker, 1 Angiotensin II receptor antagonist, 6 other medications including cardiotonic and vasodilative agent).