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cardiotonic |
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cardiotonic /car·dio·ton·ic/ (kahr″de-o-ton´ik) having a tonic effect on the heart; an agent that so acts.
cardiotonic [kär′dē·ōton′ik] Etymology: Gk, kardia + tonos, tone 1 pertaining to a substance that tends to increase the efficiency of contractions of the heart muscle. 2 a pharmacologic agent that increases the force of myocardial contractions. Cardiac glycosides, derived from certain plant alkaloids, exert a tonic effect by altering the transport of electrolytes across the myocardial membrane, causing a decreased efflux of sodium and calcium and a decreased influx of potassium. Digitoxin and digoxin, widely used cardiac glycosides obtained from leaves of a species of foxglove, increase the force of myocardial contractions, extend the refractory period of the atrioventricular node, and, to a lesser degree, affect the sinoatrial node and the heart's conduction system. cardiotonic, adj/n property of a substance that has an invigorating effect on the heart. cardiotonic having a tonic effect on the heart; an agent that so acts. cardiotonic adjective Referring to a tonic effect on the heart noun An agent with said effect–eg, digitalis How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The chemical isolate obtained from a subspecies of foxglove is called digitoxin, a powerful cardiotonic glycoside (heart stimulant) used to treat heart failure and certain forms of irregular heartbeat. |
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