We hypothesised, that in patients with EF <35% undergoing coronary revascularisation with cardiopulmonary bypass, that markers of myocardial and endothelial damage, as well as LV function would be preserved with L-arginine blood cardioplegic arrest when compared to standard blood cardioplegia treatment alone.
Secondary outcome variables were measured in order to determine mechanisms and functional action of L-arginine cardioplegic arrest.
The method used for short-term preservation consists of initial cardioplegic arrest of the donor heart with a hyperkalaemic and hypertonic solution, together with topical cooling of the myocardium.
After cardioplegic arrest of the heart and topical cooling of both donor organs, the pulmonary artery and veins were ligated and divided.
Especially cardioplegic arrest
of the heart in high-risk situations as elderly patients, compromised ventricle, re-operations and high PAP may make weaning from the CPB problematic.
The C-Port Flex A system has the potential to revolutionize the field of cardiothoracic surgery, as it may enable closed-chest, robot-assisted CABG procedures to be more reliably performed without the assistance of cardiopulmonary bypass and cardioplegic arrest
of the heart," added Dr.
In the present study, the levels of NO released from the coronary vasculature before cardioplegic arrest and after reperfusion were compared between two groups of diabetic patients receiving different cardioplegic solutions.
Our data show that, during cardioplegic arrest provided by crystalloid cardioplegia the release of NO from the coronary vasculature decreased significantly compared to blood cardioplegia.
Our institutional routine is to use cold cardioplegic arrest
, but in this child, the VSD was closed using normothermic CPB under fibrillatory arrest, in order to avoid hypothermia during the brief cross-clamp time that was expected for the procedure.
The effect of L-arginine on myocardial recovery after cardioplegic arrest
and ischemia under moderate and deep hypothermia.
However, recent evidence from two small studies suggests that plasma concentrations of BNP are elevated after open cardiac surgery and cardioplegic arrest
The importance of glucose-insulin-potassium with cardiopulmonary bypass prior to cardioplegic arrest
in open-heart surgery.