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Chief or principal; in embryology, relating to the main venous drainage.
[L. cardinalis, principal]


/car·di·nal/ (kahr´dĭ-n'l)
1. of primary or preeminent importance.
2. in embryology, pertaining to the main venous drainage.


Etymology: L, cardo, hinge
pertaining to something so fundamental that other things hinge on it, such as a cardinal trait that influences one's total behavior.


A gene on chromosome 19q13.33 that encodes a protein involved in apoptosis which is highly expressed in the lung, ovary, testis and placenta. CARD8 inhibits NF-kappa-B activation and regulates cell responses controlled by NF-kappa-B transcription factor. It may be part of the inflammasome, a protein complex that activates proinflammatory caspases.
References in periodicals archive ?
In contrast, the cardinally quantifying subject there in (78) points to its complement spaghetti as an enumerating complement.
The first aspect of Walras's conception of a capitalist economy, as defined by Walker, is the idea that all economic agents strive to maximize their cardinally measurable utility.
u]tility is measurable, ordinally or cardinally, only to the individual decision-maker.
At bottom, any assertion that it is conceptually or logically impossible to rank ordinally or cardinally alternative goods is an assertion that, as constructed by us, the goods cannot be ranked meaningfully.
He gives precise conditions for the various measurability assumptions (preferences are ordinally, cardinally, or fully measurable; with, or without, interpersonal comparability), and shows how varying those conditions and adding certain others can lead to an impossibility result, to utilitarianism, or to maximin.
One interpretation of these results is that the seriousness of deaths from specified causes was represented ordinally in respondents' minds (as shown by the high correlation) but was not represented cardinally (as shown by the identical factors).
In cases where one party will be much worse off by far than the other if not helped, but the outcome this party can look forward to is much worse than what the other faces, the most we should do is multiply whatever other items besides need (such as outcome or urgency) are relevant to distribution by a factor that varies cardinally with the degree of need in order to give the neediest an edge.
Finally, for both these policy changes, the household data are grouped into legislative districts to determine whether state senators' decisions to support or oppose the reforms enacted in 1990 and their partial repeal in 1991 reflect the economic interests of households calculated either cardinally (the mean voter, dollar-weighted) or ordinally (the median voter).
Elbow: Marry, sir, by my wife, who, if she had been a woman cardinally given, might have been accused in fornication, adultery, and all uncleanliness there.
A cardinally significant Atkinson-Kolm-Sen relative index of inequality reflecting that perspective is proposed and computed from the full HIES data series for the years 1984-85, 1985-86, 1986-87, and 1987-88.
LM assumes that individuals perceive their welfare cardinally, in a way that tells something about intensity of feeling.
The Orrefors Kosta Boda group has developed according to the expectations with cardinally lower external costs, increased sales and a profit for the whole year.