cardinal symptom


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car·di·nal symp·tom

the primary or major symptom of diagnostic importance.

cardinal symptom

See symptom.

car·di·nal symp·tom

(kahr'di-năl simp'tŏm)
The primary or major symptom of diagnostic importance.

cardinal symptom

A fundamental symptom of a disease.
See also: symptom
References in periodicals archive ?
TZP-102's effects on symptom severity were evaluated by a validated patient-reported outcome (PRO) instrument, the Patient Assessment of Gastrointestinal Symptoms scale (PAGI-SYM), and the Gastroparesis Cardinal Symptom Index (GCSI) after 8, 15, and 28 days of treatment.
a cardinal symptom of SAHS in the absence of diuretic therapy and excessive fluid intake or overload.
1ua2] >79 min (1 SD above normal; with 75% of patients >2 SD above normal), Gastroparesis Cardinal Symptom Index greater than or equal to 2.
The fourth cardinal symptom of PD is postural instability, which is related to rigidity.
They list the cardinal symptom as post-exertional neuroimmune exhaustion.
Early CT may therefore be important in ruling out CRS as the cause of facial pain in those in whom this is the cardinal symptom.
The Gastroparesis Cardinal Symptom Index (GCSI) was used to measure symptom severity.
We put in a cardinal symptom that you cannot ignore, which is rectal bleeding.
In patients who reported complete resolution of one cardinal symptom there was an average improvement in endoscopy scores of 12%.
This interim blinded data shows that approximately 20% of all patients are achieving the primary endpoint of complete resolution of both cardinal symptoms and another 23% of patients are achieving complete resolution of one or the other cardinal symptom at 16 weeks.
Debilitating bone pain is the cardinal symptom of this stage of the disease and there are currently limited choices to delay this in men.