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contractility
(redirected from cardiac contractility)

   Also found in: Dictionary/thesaurus, Wikipedia 0.01 sec.
contractility /con·trac·til·i·ty/ (kon″trak-til´ĭ-te) capacity for becoming shorter in response to a suitable stimulus.
contractility
[kon′traktil′itē]
the ability of muscle tissue to contract when its thick (myosin) and thin (actin) filaments slide past each other.

contractility [kon″trak-til´ĭ-te]
a capacity for shortening in response to suitable stimulus.

contractility
a capacity for becoming short in response to suitable stimulus.

cardiac contractility
the inotropic state of the myocardium; a major determinant of cardiac output and an important factor in cardiac compensation.


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In order to improve the hemodynamic profile of the heart and increase cardiac contractility, a physician may also administer an intravenous inotropic agent such as dobutamine (beta-adrenergic agonist) or milrinone (PDE3- inhibitor).
The main regulator of SERCA2a is phospholamban, which has been accepted as a key regulator of SERCA2a and cardiac contractility.
Spindler and his research team used Affymetrix microarrays as well as biochemical and histological studies to show that CR rapidly changes cardiac gene expression and physiology to reduce cardiovascular damage, fibrosis, and blood pressure, and to enhance cardiac contractility and energy production.
 
 
 
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