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carcinogenesis

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.
car·ci·no·gen·e·sis (kärs-n-jn-ss)
n.
The production of cancer.

carcinogenesis
[kär′sinəjen′əsis]
the process of initiating and promoting cancer. Compare malignant transformation, oncogenesis, sarcomagenesis, tumorigenesis.

carcinogenesis
production of cancer.

biological carcinogenesis
viruses and some parasites are capable of initiating neoplasia. See viral oncogenesis, Spirocercalupi.
chemical carcinogenesis
numerous chemicals have been identified as carcinogenic.
physical carcinogenesis
includes ultraviolet radiation, ionizing radiation and asbestos.

carcinogenesis
Transformation, tumourigenesis Oncology A series of genotypic and phenotypic changes that result in a cell being identified as malignant by virtue of its metastatic potential. See Cancerization, Chemical carcinogenesis, Inducer, One-hit/two-hit model, Proto-oncogenes, Tumor promoter, Tumor suppressor.


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To explore further the molecular mechanisms of transplacental arsenic hepatocarcinogenesis, we conducted a second arsenic transplacental carcinogenesis study and used a genomewide microarray in profile arsenic-induced aberrant gene expression more extensively.
Harris, chief of the Human Carcinogenesis Laboratory at the National Cancer Institute in Bethesda, Md.
The research, published in the journal Carcinogenesis, was conducted with pregnant mice and revealed that a chemical found in Sauerkraut - Indole-3-carbinol - gave their offspring noticeable protection against leukemia and lymphoma at a young age, and against lung cancer later in life.
 
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