carboxypenicillin


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carboxypenicillin

a group of antipseudomonal penicillins which include carbenicillin and ticarcillin.
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Clinical isolates have been shown to constitutively produce [beta]-lactamases, which confer resistance to both amino- and carboxypenicillins and allow the organism to survive antibiotic therapy and initiate infection.
If these microorganisms are human pathogens, they will influence the choice of antimicrobial drugs for empiric treatment because most are resistant to carboxypenicillins, ureidopenicillins, third-generation cephalosporins, and fluoroquinolones, which are commonly used in the ICU.