carboxyhaemoglobin


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Related to carboxyhaemoglobin: carbon monoxide poisoning, methemoglobin, carboxyhemoglobin test

car·box·y·he·mo·glo·bin

(kahr-bok'sē-hē'mŏ-glō'bin)
A stable union of carbon monoxide with hemoglobin. The formation of carboxyhemoglobin prevents the normal transfer of carbon dioxide and oxygen during the circulation of blood; thus, increasing levels of carboxyhemoglobin result in various degrees of asphyxiation, including death.
Synonym(s): carbon monoxide hemoglobin, carboxyhaemoglobin.

carboxyhaemoglobin

The stable compound formed between CARBON MONOXIDE and HAEMOGLOBIN that does not readily dissociate. As a result, the oxygen carrying power of the blood is limited. A high level of carboxyhaemoglobin is the cause of death in carbon monoxide poisoning as from car exhaust.

carboxyhaemoglobin

a stable compound produced when carbon monoxide combines irreversibly with HAEMOGLOBIN in the red blood cells, giving the blood a bright red colour. A consequence of the reaction is that haemoglobin is less able to combine freely with oxygen. This can lead to poisoning by lack of oxygen in the blood and eventually death if there is sufficient carbon monoxide in the atmosphere.
References in periodicals archive ?
Carboxyhaemoglobin and methaemoglobin findings in burnt bodies.
Study on the effects of heat on blood and on the post-mortem estimation of carboxyhaemoglobin and methaemoglobin.
50 The advantages of cessation include: (i) slowing of the rate of decline of lung function (a small initial improvement in spirometry occurs in some), (ii) improved oxygen transport in blood, through reductions in carboxyhaemoglobin and blood viscosity, (iii) reduced tendency to thrombosis, (iv) improvements in appetite, body mass, muscle strength and exercise tolerance, (v) possible improved efficacy of some classes of drugs used in COPD, and (vi) delayed development of respiratory failure and cor pulmonale.
When the gas mixes with haemoglobin - a component of red blood cells - it produces carboxyhaemoglobin, a substance that swells the brain, causing unconsciousness and nerve damage.
Blood carboxyhaemoglobin levels in Indian bidi and cigarette smokers.
Increase blood carboxyhaemoglobin concentrations in inflammatory pulmonary diseases.
The carboxyhaemoglobin (COHb) level in the blood (half-life 2 - 6 hours) after inhalation of CO will depend on concentrations of inspired CO, duration of exposure, pulmonary ventilation and the COHb level before the inhalation.
1988, Blood carboxyhaemoglobin levels following acute exposure to smoke of biomass fuel.
Useful laboratory test: Blood gases including carboxyhaemoglobin level.