Current recommendation for the standardization of BTM measurements in future studies is to use serum carboxy terminal
telopeptide of collagen type I (s-CTX) as the standard bone resorption marker and serum procollagen type I N-terminal propeptide (P1NP) as the standard bone formation marker .
While NMDARs have been reported to be synaptic or perisynaptic, developmental replacement of G1uN2B by GluN2A at hippocampal synapses (Barria and Malinow, 2002) depends on the match between the cytoplasmic carboxy terminal
domain of GluN2 and the predominant MAGUK expressed at a given postnatal age (Sheng, 2001; Kiihr, 2006).
Confirmation of Peptan benefits on bone health was obtained by the measures of Carboxy Terminal
Telopeptide (CTX), a usual marker of bone resorption.
The cleavage motif was modified with a carboxy terminal
6xHis-tag (Table 1) to enable the selective extraction of cleaved reporter peptide fragments from serum specimens (15).
Endoproteases of the Subtilisin-like Proprotein Convertase (SPC) family cleave substrate proproteins on the carboxy terminal
side of a conserved sequence described as N-Arginine-X-X-Arginine-C.
1] cell membranes using an antibody specific to the unique carboxy terminal
domain of the P2X7 receptor.
Subsequently, a PCR assay (PCR 2) was developed using a commercially available primer and a virus-specific primer which amplified a fragment of ~600 bp that covered both the carboxy terminal
of the viral coat protein and the 3' UTR of the virus.
4] Nonstandard abbreviations: PTH, parathyroid hormone; ALP, alkaline phosphatase; P1NP, N-terminal propeptide of type I collagen; P1CP, carboxy terminal
propeptide; PaTH, Parathyroid Hormone and Alendronate for Osteoporosis study; BMD, bone mineral density; CTX, carboxy-terminal telopeptide of type I collagen; LSC, least significant change.
Calmodulin binds to the intracellular carboxy terminal
of the [Alpha]1C subunit.