carbon monoxide diffusing capacity


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carbon monoxide diffusing capacity

A clinical test which provides an objective measure of lung function. It reflects the lung's ability to take up an inhaled nonreactive test gas—e.g., carbon monoxide (CO)—which binds to haemoglobin with such a high affinity that virtually all of the CO reaches the alveolar space. The CO crosses the alveolar air-blood barrier, reaching the red cells, binds to haemoglobin and is removed with the exhaled gas.
References in periodicals archive ?
Pulmonary function testing revealed reduced lung volumes, including forced ventilatory capacity (46% of predicted), forced expiratory volume in 1 sec (54% of predicted), total lung capacity (53% of predicted), functional residual capacity (43% of predicted), and carbon monoxide diffusing capacity (36% of predicted).
The most current standards are the 1995 ATS standards (Single-breath carbon monoxide diffusing capacity (Transfer Factor): Recommendations for a standard technique--1995 Update.
Those with a forced expiratory volume in 1 second 20% or less of predicted value and either homogeneous distribution of emphysema on CT scan or low carbon monoxide diffusing capacity that is 20% or less of predicted value.