CHST4

(redirected from carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4)

CHST4

A gene on chromosome 16q22.2 that encodes a sulfotransferase which catalyses the transfer of sulfate to residues within mucin-associated glycans. These glycans serve as L-selectin ligands, which are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing to sites of inflammation.

Molecular pathology
CHST4 is expressed in colonic mucinous adenocarcinoma.
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