carbachol


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carbachol

 [kahr´bah-kol]
a cholinergic agonist that is not hydrolyzed by acetylcholinesterase or pseudocholinesterase; it is used as a miotic and to lower intraocular pressure in treatment of glaucoma and after cataract surgery.

carbachol

/car·ba·chol/ (kahr´bah-kol) a cholinergic agonist used as a miotic and to lower intraocular pressure in the treatment of glaucoma and following cataract surgery.

carbachol

A cholinergic agonist, which acts on muscarinic and nicotinic receptors. It is used in ophthalmology to manage glaucoma and in ophthalmic surgery.

Contraindications
Carbachol’s parasympathomimetic effect precludes its use in patients with asthma, bradycardia, hypotension, coronary artery disease, peptic ulcers and urinary incontinence.

carbachol

A parasympathomimetic formed by substituting an acetyl with a carbamyl group on acetylcholine, which acts on muscarinic and nicotinic receptors

carbachol

A drug with ACETYL CHOLINE-like properties of stimulating the PARASYMPATHETIC NERVOUS SYSTEM. It is used to stimulate PERISTALSIS in the intestine, to treat retention of urine and sometimes to treat GLAUCOMA.

parasympathomimetic drug 

A drug with an action resembling that caused by stimulation of the parasympathetic nervous system. Example: a miotic of which there are two types: a direct-acting cholinergic, such as pilocarpine or carbachol; and the other, indirect-acting anticholinesterase, such as physostigmine, neostigmine, echothiophate iodide, demecarium bromide. Syn. cholinergic drug. See miotics.

carbachol

a potent choline ester with muscarinic and nicotinic effects including defecation, slowing of the heart, urination and respiratory restriction due to bronchiolar constriction.
References in periodicals archive ?
Subjecting the animals to RS or to NMS reduced the responsiveness of the stomach fundus preparation to carbachol significantly (p < 0.
70) The muscarinic receptor agonist carbachol did not significantly affect myopic growth induced by form deprivation in the chick.
Prior to carbachol challenge, each child performed baseline pulmonary function tests.
The hESC-derived smooth muscle expressed SMC-specific markers (-SM actin and calponin) and contracted upon stimulation with carbachol," stated Shi-Jiang Lu, first author of the paper.
c) Treatment with STW5 resulted in statistically significant protection against the reduction in responsiveness to adrenaline, carbachol and serotonin in both the RS and NMS/RS models
The aim of this study was to examine the effects of trimetazidine on ischemic preconditioning and carbachol preconditioning in anesthetized rats.
After ozone exposure, bronchial rings derived from mindin-/- mice demonstrated reduced constriction in response to carbachol.
2] influx into these isolated adrenal medullary cells, but has a profound effect on the action of carbachol (which mimics the action of the normal transmitter at this splanchnic synapse: acetylcholine) and on the influx which is induced by the depolarising action of 77 mM [K.
Carbachol, a muscarinic agonist, appropriately reduced both the basal and isoprenaline-induced contractile frequency, demonstrating appropriate muscarinic receptor activity as well.
This new compound was shown to inhibit the gastric acid secretion induced either by histamine or carbachol in rabbit gastric glands (Biondo et al.
Pulmonary function tests showed a reduced diffusing capacity of 67% predicted with oxygen desaturation on ambulation (Table 1), and a carbachol challenge (a test for airway hyperreactivity in asthma) was negative.