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carbachol |
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carbachol /car·ba·chol/ (kahr´bah-kol) a cholinergic agonist used as a miotic and to lower intraocular pressure in the treatment of glaucoma and following cataract surgery. carbachol a potent choline ester with muscarinic and nicotinic effects including defecation, slowing of the heart, urination and respiratory restriction due to bronchiolar constriction. |
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Pulmonary function tests showed a reduced diffusing capacity of 67% predicted with oxygen desaturation on ambulation (Table 1), and a carbachol challenge (a test for airway hyperreactivity in asthma) was negative. Carbachol, a muscarinic agonist, appropriately reduced both the basal and isoprenaline-induced contractile frequency, demonstrating appropriate muscarinic receptor activity as well. Airway responsiveness to carbachol was determined from cumulative concentration-response curves as previously described (Abraham et al. |
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carbachol
