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capsid

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capsid /cap·sid/ (kap´sid) the shell of protein that protects the nucleic acid of a virus; it is composed of structural units, or capsomers.
cap·sid (kpsd)
n.
The protein shell that surrounds a virus particle.

Capsid
The outer protein coat of a virus.
Mentioned in: Noroviruses

capsid
[kap′sid]
Etymology: L, capsa, box
the layer of protein enveloping the genome of a virion. A capsid is composed of structural units called capsomeres. Its symmetry may be cubic or helical.

capsid [kap´sid]
the shell of protein that protects the nucleic acid of a virus; it is composed of structural units, or capsomers. According to the number of subunits possessed by capsomers, they are called dimers (2), trimers (3), pentamers (5), or hexamers (6).

capsid
the shell of protein that protects the nucleic acid of a virus; it is composed of individual morphological units called capsomers. For icosahedral viruses, there are two kinds of capsomers called pentamers, which occupy the 12 corner positions of the icosahedral shell, and hexamers, which occupy the face and edges. The number of hexamers varies between different viruses. The capsomers of helical viruses are composed of a single polypeptide and are also called protomers. All viruses of animals, except for poxviruses which have a complex structure, are minimally composed of a nucleocapsid which is the capsid surrounding the nucleic acid. In addition some viruses have an envelope surrounding the nucleocapsid.


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During the study, they used a combination of nuclear magnetic resonance and cryoEM, which are standard structural biology tools, to see both the overall shape and the atomic details of capsid protein (CA) assembly.
HIV assembly is a two-stage process involving an intermediate immature capsid that undergoes a morphologically dramatic maturation step after budding from the CD4 cell to yield the new infectious particle (see Figure 2).
 
 
 
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