capreomycin


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capreomycin

 [kap″re-o-mi´sin]
a polypeptide antibiotic produced by Streptomyces capreolus, which is active against human strains of Mycobacterium tuberculosis; used as the disulfate salt.

capreomycin

/cap·reo·my·cin/ (kap″re-o-mi´sin) a polypeptide antibiotic produced by Streptomyces capreolus, which is active against human strains of Mycobacterium tuberculosis ; used as the disulfate salt.

capreomycin

(kăp′rē-ō-mī′sĭn)
n.
An antibiotic that is derived from a bacterium (Streptomyces capreolus) and is used in its sulfate form to treat tuberculosis.

capreomycin

[kap′rē·ōmī′sin]
an antibiotic and antitubercular agent.
indications It is prescribed in the treatment of pulmonary infections caused by capreomycin-susceptible strains of Mycobacterium tuberculosis when the primary agents are ineffective or cannot be used.
contraindications Known sensitivity to this drug prohibits its use. It must be used with caution in patients with preexisting renal or auditory impairment.
adverse effects Among the most serious adverse reactions are nephrotoxicity, hearing loss, tinnitus, vertigo, leukocytosis, leukopenia, urticaria, and skin rash.

capreomycin

An aminoglycoside-related cyclic peptide antibiotic used in combination with streptomycin and other agents to treat Mycobacterium avium complex and M tuberculosis.

Adverse effects
Nephrotoxicity, ototoxicity and hearing loss, anorexia, thirst, excess urination, haematuria, anaemia.

capreomycin

Infectious disease An antibiotic used to treat MAC and TB Side effects Anorexia, thirst, excess urination, hematuria, anemia, hearing loss. See AIDS.

capreomycin

An antibiotic drug derived from Streptomyces capreolus and used in the treatment of TUBERCULOSIS resistant to standard drugs such as RIFAMPICIN, ISONIAZID, ETHAMBUTOL and STREPTOMYCIN. The drug is on the WHO official list. A brand name is Capastat.
References in periodicals archive ?
Molecular genetics of Mycobacterium tuberculosis resistant to aminoglycosides and cyclic peptide capreomycin antibiotics in Korea.
The intensive phase of treatment with capreomycin should be at least 8 months (8)
The same approach should be used in patients on capreomycin during the intensive phase of XDR TB treatment.
XDR-TB is defined as an MDR-TB strain with additional resistance to any fluoroquinolone and any one of the three injectable second-line drugs: capreomycin, kanamycin, and amikacin (15).
treat MDR-TB, capreomycin (CapastatA') and cycloserine (SeromycinA'), to
He was touring Speke pharmaceutical company Eli Lilly to see improvements to the production line that will make the drug Capreomycin.
Eosinophilia: gold, allopurinol, 5-ASA, ampicillin, tricyclics, capreomycin, carbamazepine, digitalis, phenytoin
Second-line drugs--with little or no scientific evidence to support their use--include cycloserine, ethionamide, streptomycin, amikacin/kanamycin, capreomycin, paminosalicylic acid, levofloxacin, moxifloxacin, and gatifloxacin.
The key market players covered are isoniazid, rifampin, pyrazinamide, ethambutol, streptomycin, rifabutin and capreomycin.
Second-line injectable drugs were kanamycin, amikacin, and capreomycin.
Choose an injectable agent Kanamycin (if susceptible) Amikacin Capreomycin 3.
Until that time, Lilly manufactured and supplied nominal quantities of two TB medicines C capreomycin and cycloserine.