caprate


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cap·rate

(kap'rāt),
A salt or ester of capric acid.

cap·rate

(kap'rāt)
A salt or ester of capric acid.
References in periodicals archive ?
5, 100 mg/kg sodium caprate and 50 mg/kg water-soluble chitosan displayed the largest AUC values in three groups; on the other hand, 25 mg/kg sodium caprate did not improve the absorption of FTA so much.
It was shown that sodium caprate at concentrations up to 0.
The total amount of protein and the activity of LDH in the presence of 5, 10, 20[micro]g/m1 water-soluble chitosan, 5, 10, 20 [micro]g/m1 sodium caprate were almost the same levels compared to PBS, although there was a remarkable increase in the amount of protein and the activity of LDH after perfusing 800[micro]g/m1 sodium caprate or 2% Triton X-100 as a positive control.
The results clearly indicated that 25, 50, 100 mg/kg sodium caprate and 25, 50, 100 mg/kg water-soluble chitosan did not cause any significant change in the morphology of the gastrointestinal membrane, although we found that above 100 mg/kg sodium caprate could cause mucosal damage, the result was consistent with the previous report shown by Motlekar et al.
Nucleo-apical distance in the presence of 25, 50, 100 mg/kg sodium caprate and 25, 50, 100 mg/kg water-soluble chitosan was not significantly decreased in duodenum, jejunum and ileum, although there was a remarkable decrease in nucleo-apical distance after administrating orally 200 mg/kg Triton X-100 as a positive control.
The result indicated that villi/crypt index in the presence of 25, 50, 100 mg/kg sodium caprate and 25, 50, 100 mg/kg water-soluble chitosan was not obviously decreased in duodenum, jejunum, ileum and colon, although there was a remarkable decrease in nucleo-apical distance after administrating orally 200 mg/kg Triton X-100 as a positive control.
We also found that the absorption enhancing effect of sodium caprate and water-soluble chitosan for improving the intestinal absorption of [-TA was affected by their concentrations, and the absorption of FTA increased with increased concentrations of sodium caprate (Table 1 and Figs.
6,5, 10, 2014/m1 chitosan and 5, 10,20 [micro]g/ml sodium caprate did not increase the amount of protein and the LDH activity although we observed a significant increase in these biological markers in the presence of 800 [micro]g/ml sodium caprate or 2% Triton X-100, as a positive control.
The present study also demonstrated that the absorption of FTA in weeping forsythia extract can be not only improved greatest, but also safety in gastrointestine by sodium caprate at dosage of 100 mg/kg and water-soluble chitosan at dosage of 50 mg/kg, respectively.