capillary zone electrophoresis


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cap·il·lar·y zone e·lec·tro·pho·re·sis (CZE),

a method for separating molecules extremely rapidly based on their electrophoretic mobility.

capillary zone electrophoresis

A rapid, sensitive and efficient high-resolution method for separating proteins, nucleic acids, carbohrates and bacteria, which is used in analytical chemistry, biomedical research, diagnostics, environmental science, food science, forensic science and toxicology. CZE separates ions based on their charge and frictional forces within a fine bore (< 1-mm diameter) capillary. CZE is sensitive in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis.
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References in periodicals archive ?
2,9,11,13,15) Capillary zone electrophoresis is at least equivalent to AGE, and the interpretation of its electrophoregrams is similar to that for AGE.
Effect of piperacillin-tazobactam on clinical capillary zone electrophoresis of serum proteins.
Quantitation of Li+ in serum by capillary zone electrophoresis with an on-column conductivity detector.
Interferences in clinical capillary zone electrophoresis of serum proteins.
Capillary zone electrophoresis (CZE) performed on "clinical" analyzers effectively detects monoclonal components (MCs) (1-4) in human serum.
Diagnosis of congenital disorders of glycosylation by capillary zone electrophoresis of serum transferrin.
Capillary zone electrophoresis (CZE) with dynamically coated capillaries and direct ultraviolet detection at 200 nm (11-17) has also been successfully applied to CDT determination in human serum (2), and a CZE method with a proprietary capillary coating is commercially available (CEofix[R] CDT; Analis).
Capillary zone electrophoresis with a dynamic double coating for analysis of carbohydrate-deficient transferrin in human serum: impact of resolution between disialo- and trisialotransferrin on reference limits.
1) recently published the first report describing the use of capillary zone electrophoresis (CZE) coupled with immunosubtraction to detect and characterize low concentrations of free [gamma] heavy chains in serum.
Carbohydrate-deficient transferrin (CDT) measured by capillary zone electrophoresis (CZE), particularly asialo-transferrin (TO, is purported to better differentiate between excessive and moderate drinkers than does CDT measured by turbidimetric immunoassay (TIA) (1, 2).
Multicenter evaluation of the Paragon CZE 2000 capillary zone electrophoresis system for serum protein electrophoresis and monoclonal component typing.