capcytobine

capcytobine

A prodrug of the chemotherapeutic 5-fluorouracil (5-FU), which is used to treat metastatic breast and colorectal cancers. 5-FU inhibits DNA synthesis and slows tumour proliferation.

Adverse effects
EKG changes, acute myocardial infarction, angina, hand-foot syndrome, pain, paraesthesia, erythema, palmoplantar blistering, diarrhoea, nausea, stomatitis, pancytopaenia, hyperbilirubinaemia.