The molecular functioning of DUB3 therefore presented the gene as a likely novel candidate gene
for the KWE phenotype.
Recently, a positional candidate gene
on SSC5, PTHLH (parathyroid hormone-like hormone), was investigated for the relationship with teat numbers.
These include (1) multigene panels for a variety of inherited disorders and oncology conditions (2-7); (2) human leukocyte antigen locus characterization (8-10); (3) pathogen genome sequencing for identification and assessment of resistance (11,12); (4) exome sequencing for candidate gene
discovery in inherited disorders and characterization of the mutational landscape in tumors (13-16); and (5) whole genome sequencing.
These so-called candidate gene
studies have been fruitful in alcohol research.
Amongst RAAS genes studied till date, CYP11B2 gene (CYP11B2) encoding aldosterone synthase has emerged as a strong candidate gene
By using such a relationship, investigators can filter candidate gene
lists and focus on those genes that most likely are associated with a causal relationship.
This is the first time someone has identified a candidate gene
for autism, replicated their finding, and demonstrated that gene's biological function," remarks geneticist Daniel H.
LANCASTER - Mayoral candidate Gene
Gaynor said he filed a police report regarding the theft and vandalism of his campaign signs.
clinical) analysis, correlations with other distinct genetic disorders, and candidate gene
The human homolog of insect-derived growth factor, CECR1, is a candidate gene
for features of cat eye syndrome.
Tuberous Sclerosis (TSC) has been found to be a candidate gene
for autism by linkage study analysis and can be found on chromosomes 9q34 (TSC 1) and 16p 13 (TSC 2).
For example, disruption of a candidate gene
should abolish the ability of the mutated pathogen to elicit disease in an animal model of infection, and reintroduction of the wild-type gene should reestablish virulence.