cancer susceptibility

cancer susceptibility

An inherent proneness toward suffering from cancer.

Fringe oncology
Advocates of unproven methods of cancer care may evoke psychoneuroimmunology arguments that certain personality types or individuals with specific mental health profiles are at an increased risk of acquiring cancer.

Cancer Susceptibility—fringe oncology arguments
• Maternal domination;
• Immature sexual adjustment;
• Inability to express emotions and hostility; 
• Inability to accept significant losses;
• Pre-neoplastic feelings of despair, hopelessness and self-pity;
• Poor self-image and interpersonal relationships;
• Lack of closeness to parents.

Mainstream oncology
A tangible risk of suffering cancer, based on chromosome and DNA analysis.
References in periodicals archive ?
In this study, the researchers demonstrate that common breast cancer susceptibility alleles with small individual effects on risk can be identified, so that combinations of lower-penetrance variants can be used to assess much of the remaining genetic risk.
As the NPL Pink Pack program enters its third successful year with BCRF, the 2012 donation will not only fund a new researcher's work to fight breast cancer, but also will be able to renew support to two other BCRF grants funded in past years; one focused on alleviating negative side effects from breast cancer treatment, and the other working towards developing drugs to prevent breast cancer in those with the BRCA-mutation (the breast cancer susceptibility gene).
London, Aug 23 (ANI): Scientists have purified the protein produced by the breast cancer susceptibility gene BRCA2 and used it to study the oncogene's role in DNA repair.
OBJECTIVES: Because both TCDD and diet affect the estrogen pathway, we examined how TCDD and a high-fat diet (HFD) interact to alter breast cancer susceptibility.
adults are aware that genetic tests exist that can identify people with inherited cancer susceptibility, based on a survey of more than 27,000 people.
In large families with several affected individuals, linkage studies can be performed to determine whether a cancer susceptibility trait is linked to one of the known BRCA genes.
Advances driven by proteomics and bioinformatics are enabling researchers to identify markers of cancer susceptibility and precancerous lesions.
The current NPL-funded BCRF grant is supporting two researchers who are trying to develop a drug that will prevent breast cancer in those with mutations in the BRCA gene (the breast cancer susceptibility gene) before it occurs as a detectable lump.
Washington, March 17 (ANI): Scientists at the University of California, San Francisco researchers have found that a key cellular defect that disturbs the production of proteins in human cells can lead to cancer susceptibility.
Many members of these pathways have been implicated in cancer susceptibility (Han et al.
From the work, it is hoped that it will be possible in the future to design and validate biomarkers associated with prostate cancer susceptibility and disease progression, as well as to facilitate development of improved therapeutic approaches.
Susan Bates and Christina Annunziata analysed numerous recent papers on this form of treatment, which takes advantage of the synthetic lethality of BRCA (breast cancer susceptibility genes) and poly-ADP ribose polymerase (PARP) proteins to attack cancerous cells even as it spares healthy ones.

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