cancer susceptibility

cancer susceptibility

An inherent proneness toward suffering from cancer.

Fringe oncology
Advocates of unproven methods of cancer care may evoke psychoneuroimmunology arguments that certain personality types or individuals with specific mental health profiles are at an increased risk of acquiring cancer.

Cancer Susceptibility—fringe oncology arguments
• Maternal domination;
• Immature sexual adjustment;
• Inability to express emotions and hostility; 
• Inability to accept significant losses;
• Pre-neoplastic feelings of despair, hopelessness and self-pity;
• Poor self-image and interpersonal relationships;
• Lack of closeness to parents.

Mainstream oncology
A tangible risk of suffering cancer, based on chromosome and DNA analysis.
References in periodicals archive ?
BRCA mutation testing for breast and ovarian cancer susceptibility is advisable, especially if there is any family history of cancers.
Healthcare company AstraZeneca Pharmaceuticals LP reported on Friday the receipt of approval from the US Food and Drug Administration for the expanded approval for the use of Lynparza (olaparib tablets) for the treatment of patients with germline breast cancer susceptibility gene (BRCA) mutated, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer, who have been previously treated with chemotherapy.
The paper also provides a foundation for others to investigate the DNA loci and associated genes that play roles in skin cancer susceptibility and the effects of UV radiation.
The main purpose of this case study was to indicate the separate testing methodologies that are available to diagnose patients who show no other symptoms of cancer susceptibility.
Also, the earlier observations were inconsistent in terms of their roles in oral cancer susceptibility and therefore the influence of these genes polymorphisms is still unclear.
Non-secretor genotype was associated with axillary lymph node metastasis and could be useful to predict respectively breast cancer susceptibility and axillary lymph nodes metastasis.
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumorsuppressorgene in mice.
In addition, if there is a known genetic mutation associated with cancer susceptibility in the family or there are close family members with breast cancer, ovarian cancer or male breast cancer, gene testing may be appropriate, Dr.
In August 2015, ASCO released an updated policy statement on genetic and genomic testing for cancer susceptibility and highlighted five key areas: germ-line implications of somatic mutation profiling; multigene panel testing for cancer susceptibility; quality assurance in genetic testing; education for oncology professionals; and access to cancer genetic services.
Approximately 5%-10% of breast cancer cases present in individuals with inherited mutations in autosomal dominant, highly penetrant breast cancer susceptibility genes.
An ever-growing number of medical societies and expert panels have now charged clinicians with the duty to evaluate and manage their patients' cancer risk profiles, with particular attention to those individuals carrying genetic mutations that confer elevated cancer susceptibility, a process commonly known as hereditary cancer risk assessment, or HCRA.
Only a small percentage of women inherit the same faulty gene, known as BRCA1 -- the name stands for breast cancer susceptibility gene.

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