Dr Athos Gianella-Borradori, Cyclacel's medical director commented, "It is encouraging to see validation of the presumed mechanism by which CYC202 is causing the death of cancer cells
through biomarker technology.
AR expression or ligand specificity played a minimal role in this arsenic-induced prostate cancer cell
have multiple abnormalities, including DNA damage, but they are able to survive and proliferate because key checkpoints and apoptotic pathways are disabled as the cancer develops.
On the basis of these observations, we reasoned that the MCF-7 human breast cancer cell
proliferation (the E-Screen) assay (Soto et al.
Normal cells that transform into cancer cells
undergo various metabolic changes, including shifts in activities of enzymes that mediate macromolecule synthesis and growth-signaling pathways.
Others transplant tumors or inject millions of cancer cells
into the bloodstream.
Her cancer cells
seemed to be reactivated in her stressful state.
Lead author Fernando LopezDiaz, Salk staff scientist, said the team aimed to uncover the diversification "switch" by which cancer cells
replicated but vary slightly from one another and that turning off this cellular process would strip cancer's ability to survive drug treatment, Science Daily reported.
A single tumor-suppressing gene is a key to understanding--and perhaps killing--dormant ovarian cancer cells
that hide out after initial treatment, only to reawaken years later, report researchers at the University of Texas M.
The antibody serves to target the compound specifically to cancer cells
and the cytotoxic agent serves to kill those cells.
Anti-Cell Adhesive Effects of GRN163L in Cancer Cells
In 1889, Stephen Paget proposed that cancer cells
shed from an initial tumor were dispersed randomly throughout the body by the circulatory system.