calponin


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calponin

(kal-pō′nĭn)
A smooth-muscle binding protein. It is used in immunohistochemistry to identify tumors that contain myoepithelial cells, and it regulates the contraction of smooth muscle.
References in periodicals archive ?
The phenotype of the isolated cells was checked with phase contract microscopy and immunofluorescence (pancytokeratins [AE] 1/AE3 for UCs and smooth muscle actin [SMA] and calponin for BSCs and SMCs).
The participation of calponin in the cross talk between 20-hydroxyecdysone and juvenile hormone signaling pathways by phosphorylation variation.
Immunohistochemical stains for E-cadherin, myoepithelial cells (p63, calponin, and smooth muscle myosin), lymphatic endothelial cells (D2-40 and CD31), and estrogen and progesterone receptor proteins were prepared following standard immunoperoxidase protocols.
5) The myoepithelial lesions are immunoreactive with dark-brown staining for alpha-smooth muscle actin, calponin, and myosin.
However, these do not stain for smooth muscle actin and calponin.
CD99 showed weak cytoplasmic positivity, and smooth muscle actin (SMA), desmin, synaptophysin, chromogranin, S100 protein, cytokeratin AEl/AE3, CD45, CD34, CD117, calretinin, calponin,13-catenin, epithelial membrane antigen (EMA), and Cam5.
Immunolocalization of the smooth muscle-specific protein calponin in complex and mixed tumors of the mammary gland of the dog: assessment of the morphogenetic role of the myoepithelium.
In myoepithelioma, tumor cells stain positive for S-100 protein, alpha-SMA, muscle-specific actin, vimentin, pankeratin, cytokeratin 7, cytokeratin 14, GFAP, EMA, and calponin.
A recent study demonstrated that calponin was present in the olfactory fibroblast meningeal cells but not in the adult OECs [47], thus strengthening the argument that OECs can form myelin.
6,7) The myoepithelial component is highlighted by p63, smooth muscle myosin heavy chains, CK5, CD10, calponin, actin, and S100.