calpain-3

(redirected from calpain p94)

calpain-3

An intracellular, calcium-dependent, tissue-specific major cysteine protease encoded by CAPN3 on chromosome 15q15.1, the function of which is as yet not fully understood; it specifically binds to titin. 
Abnormal calpain-3 mutations have been linked to limb-girdle muscular dystrophy type 2A (LGMD2A) [MIM:253600].