calpain


Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.
Related to calpain: cathepsin, calpastatin

calpain

(kăl′pān′)
n.
A proteolytic enzyme regulated by the concentration of calcium ions.
References in periodicals archive ?
In agreement with Shackelford, Morgan, Cross and Savell (1991), several studies demonstrate the influence of pH on the activity of cathepsins and calpains, which are proteolytic enzymes, suggesting that the observed differences in pH may be partially responsible for the differences in tenderness.
Proteolytic enzymes such as cathepsins and calpains are involved in structural and biochemical changes during post mortem ageing process (Ouali et al.
17) Proteins that compose the calcium network undergo oxidative modification through time, resulting in conformational changes, aggregation, and internalization from the plasma membrane and proteolytic degradation by the calcium-activated calpains and caspases.
1) and degradation (Table 1) of A[beta] are performed by proteases and because proteases such as calpain (127) and caspase (128,129) may be involved in the downstream pathological cascade.
Carcass characteristics, the calpain proteinase system, and aged tenderness of Angus and Brahman crossbred steers.
Independent of calpain, the researchers also found that host PKC played an important role in the loss of protein adducin from the host cytoskeleton, contributing greatly to its collapse.
Physiological studies suggest that variations in calpain 10 activity effects insulin secretion, and therefore, susceptibility to T2DM.
The enzyme calpain plays a key role in this; calpain is activated by the increased calcium content of stimulated nerve cells," Breuer said.