calmodulin


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calmodulin

 [kal-mod´u-lin]
a calcium-binding protein present in all nucleated cells, thought to be an essential mediator of most calcium-sensitive cellular processes.

cal·mod·u·lin

(kal-mod'ū-lin),
A small, ubiquitous eukaryotic protein that binds calcium ions, thereby becoming the agent for many of the cellular effects long ascribed to calcium ions. This calcium-protein complex binds to the apoenzyme, to form the holoenzyme, of certain phosphodiesterases; through these mechanisms, the complex regulates adenylate and guanylate cyclases, many kinases, phospholipase A2 activity, and other basic cellular functions.
[calcium + modulate]

calmodulin

/cal·mod·u·lin/ (kal-mod´u-lin) a calcium-binding protein present in all nucleated cells; it mediates a variety of cellular reponses to calcium.

calmodulin

(kăl-mŏj′ə-lĭn)
n.
A calcium-binding protein that mediates many metabolic processes, such as contraction of smooth muscle, by binding to enzymes and other proteins.

calmodulin

[kalmod′yəlin]
a calcium-binding protein that mediates a variety of biochemical and physiological processes, including the contraction of smooth muscles and the release of norepinephrine. Calmodulin may act independently of, in concert with, or antagonistically to reactions involving cyclic adenosine monophosphate.

cal·mod·u·lin

(kal-mod'yū-lin)
A protein that binds calcium ions, thereby becoming the agent for many of the cellular effects long ascribed to calcium ions.
[calcium + modulate]

cal·mod·u·lin

(kal-mod'yū-lin)
Protein that binds calcium ions.
[calcium + modulate]

calmodulin (kalmoj´əlin),

n a calcium-binding protein that mediates a variety of biochemical and physiologic processes, including the contraction of muscles and the release of norepinephrine.

calmodulin

a calcium-binding protein concerned in the response of muscle fibers and other cells to calcium.
References in periodicals archive ?
Protein-serine/threonine kinases, myo-inositol-1-phosphate synthases and calmodulins, as the members of ABA and IP3/Ca2+ signal transduction pathway, played an important role in the low temperature stress.
The downstream components; mitogen-activated protein kinases, Hsp90 and calmodulins are involved in the activation of Heat-shock transcription factors (Hsf).
Because the stimulation was abolished by the calmodulin in the presence of [Ca.
Glyoxalase I from Brassica juncea is a calmodulin stimulated protein.
The effects of calmodulin kinase II inhibitor on ventricular arrhythmias in rabbits with cardiac hypertrophy," Zhonghua Xin Xue Guan Bing Za Zhi, vol.
Hidaka, Modulation of calmodulin function and of Ca2+-induced smooth muscle contraction by the calmodulin antagonist, HT-74, Mol.
Another spine model with spatial detail was created using the cellular dynamics simulator to evaluate whether the two lobes of calmodulin could be differentially sensitive to calcium nanodomains within the spine (Kubota and Waxham, 2010).
The sensing protein calmodulin is a calcium-activated protein that renders graded changes in the concentration of the calcium ion into graded responses through activation of various enzymatic pathways, including local changes in membrane proteins to modulation of genetic expression.
We discovered that a genetic mutation in calmodulin causes a loss of regular heart rhythm and produces ineffective communication between calmodulin and RYR.
The pattern of almost complete absence of some protein mRNA in seedlings is also observed to other proteins different of lectins such as calmodulin from maize.
Calmodulin (CaM) is a ubiquitous calcium signaling messenger and its overexpression leads to unregulated cell growth.
Calcium ions entering the cytoplasm through plasma membrane channels like VGCCs or release from internal stores like endoplasmic reticulum, binds to small molecular weight proteins like calmodulin.