calcium pump


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to calcium pump: plasma membrane calcium pump

pump

 [pump]
1. an apparatus for drawing or forcing liquid or gas.
2. to draw or force liquids or gases.
blood pump a machine used to propel blood through the tubing of extracorporeal circulation devices.
breast pump a pump for taking milk from the breast.
calcium pump the mechanism of active transport of calcium (Ca2+) across a membrane, as of the sarcoplasmic reticulum of muscle cells, against a concentration gradient; the mechanism is driven by hydrolysis of ATP.
enteral feeding pump an infusion pump specifically designed for administration of a solution through a feeding tube.
insulin pump see insulin pump.
intra-aortic balloon pump see intra-aortic balloon pump.
muscle pump compression of veins by the contraction of skeletal muscles, forcing blood towards the heart against the flow of gravity; seen particularly in the deep veins of the lower limbs. Called also venous pump.
proton pump a system for transporting protons across cell membranes, often exchanging them for other positively charged ions.
sodium pump (sodium-potassium pump) the mechanism of active transport driven by the energy generated by Na+,K+-ATPase, by which sodium (Na+) is extruded from a cell and potassium (K+) is brought in, so as to maintain the low concentration of sodium and the high concentration of potassium within the cell with respect to the surrounding medium. A high concentration of intracellular potassium is necessary for vital processes such as protein biosynthesis, certain enzyme activities, and maintenance of the membrane potential of excitable cells. Called also Na+-K+ pump.
stomach pump see stomach pump.
venous pump muscle pump.

cal·ci·um pump

a membranal protein that can transport calcium ions across the membrane using energy from ATP.

calcium pump

a theorized, energy-requiring mechanism for transmitting calcium ions across a plasma membrane from a region of low calcium ion concentration to one of higher concentration. Compare sodium-potassium pump.

calcium pump

A calcium-pumping enzyme which is present in high concentrations (up to 90%) in the membrane of sarcoplasmic reticulum and activated by cATPase, which reduces cytoplasmic Ca2+, ends muscle contraction and allows muscle relaxation.

cal·ci·um pump

(kal'sē-ŭm pŭmp)
A membranal protein that can transport calcium ions across the membrane using energy from ATP.

pump

1. an apparatus for drawing or forcing liquid or gas.
2. to draw or force liquids or gases.
3. a mechanism or structure that mediates active transport of ions or molecules across a biological membrane.

blood pump
a machine used to propel blood through the tubing of extracorporeal circulation devices.
calcium pump
the mechanism of active transport of calcium (Ca2+) across a membrane, as of the sarcoplasmic reticulum of muscle cells, against a concentration gradient; the mechanism is driven by hydrolysis of ATP.
infusion pump
an electronic device used to control the administration of intravenous fluids in very small amounts and at a carefully regulated rate over long periods.
pump oxygenator
heart-lung machine. See extracorporeal circulatory support unit.
sodium pump, sodium-potassium pump
the mechanism of active transport driven by hydrolysis of ATP, by which sodium (Na+) is extruded from a cell and potassium (K+) is brought in, so as to maintain the low concentration of Na+ and the high concentration of K+ within the cell with respect to the surrounding medium. See also na+,k+-atpase.
stomach pump
an apparatus used to remove material from the stomach. It consists of a rubber stomach tube to which a bulb syringe is attached. The tube is inserted into the mouth or nose and passed down the esophagus into the stomach. Suction from the syringe brings the contents of the stomach up through the tube. For cattle and horses a reversible metal pump adapted from a yachting bilge pump is most suitable. In small animals, gravity is the usual method of moving fluid into and out of the stomach during lavage.
References in periodicals archive ?
We purified the part of the calcium pump that interacts with calcium-activated calmodulin, and we managed to crystallise a protein complex.
The fact that two calmodulin proteins are involved in the regulation of the calcium pump activity means that the calcium pump has three steps.
With two calmodulin-binding domains in the calcium pump, the cell can adjust the transportation to be energy efficient, at the same time as being able to quickly reduce the number of calcium ions if the concentration approaches a toxic level,' Dr Poulsen concludes.
The researchers also used mathematical network modelling to further identify whether the calcium pump works differently depending on whether it is activated by zero, one or two calmodulin proteins.
Travel Business Review-October 23, 2012--UNIVERSITY OF COPENHAGEN - Danish researchers release ground-breaking knowledge about calcium pumps in cells(C)2012] ENPublishing - http://www.
Structural changes in the calcium pump accompanying the dissociation of calcium.
Sacroplasmic reticulum calcium pump in cardiac and slow twitch skeletal muscle but not fast twitch skeletal muscle undergoes phosphorylation by endogenous and exogenous [Ca.
21), (23) Damage to DNA, the internal lipid membrane, and to proteins occurs, reducing the efficiency of energy production and the availability of chemical energy to energize the calcium pumps of the ce11.
Collectively, the multiple defects in calcium homeostasis from the increased release of calcium from the ER, reduction in calcium extrusion through the cell membrane, the reduction in buffering capacity, and the impairment of calcium pumps, also the impairment of the mitochondrial sinks, result in changes to neuron function and cell viability.

Full browser ?