calcium levulinate

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cal·ci·um lev·u·lin·ate

a hydrated calcium salt of levulinic acid; it has the usual effects of calcium administered orally or intravenously.


a chemical element, atomic number 20, atomic weight 40.08, symbol Ca. See Table 6. Calcium is the most abundant mineral in the body. In combination with phosphorus it forms calcium phosphate, the dense, hard material of the bones and teeth. It is an important cation in intra- and extracellular fluid and is essential to the normal clotting of blood, the maintenance of a normal heartbeat, and the initiation of neuromuscular and metabolic activities.
Within the body fluids calcium exists in three forms. Protein-bound calcium accounts for about 47% of the calcium in plasma; most of it in this form is bound to albumin. Another 47% of plasma calcium is ionized. About 6% is complexed with phosphate, citrate and other anions.
Ionized calcium is physiologically active. One of its most important physiological functions is control of the permeability of cell membranes. Parathyroid hormone, which causes transfer of exchangeable calcium from bone into the bloodstream, and calcitriol maintain calcium homeostasis by preventing either calcium deficit or excess.

calcium arsenate
used extensively as a spray in orchards, constituting a poison hazard for livestock.
avian calcium poisoning
excess calcium in the avian diet, especially in diets low in phosphorus causes nephrosis, visceral gout and urolithiasis.
calcium balance
the balance between calcium intake and losses in feces and urine.
calcium borogluconate
calcium carbonate
an insoluble salt occurring naturally in bone, shells and chalk. A common form of supplementary calcium in dogs and cats on meat-based diets, used because of its high concentration of calcium (40%) and absence of phosphorus.
calcium challenge test
an intravenous infusion of calcium will cause increased levels of gastrin in dogs with a gastrinoma. Often used in combination with a secretin test.
calcium channels
see channel.
calcium chloride
a salt used in solution to restore electrolyte balance, to treat hypocalcemia and as an antidote to magnesium poisoning. Is highly irritant and has been discarded generally in favor of less irritating substances, e.g. calcium borogluconate.
calcium cyanamide
agricultural fertilizer capable of being toxic.
calcium cytosolic
see cytosol.
diffusible calcium
see calcium (above).
calcium edetate (Ca-EDTA)
calcium ethylenediamine tetra-acetic acid; the disodium and dipotassium salts are commonly used as anticoagulants in the preservation of blood samples for hematology. A chelating agent, used parenterally in the treatment of lead poisoning. See also edetate.
excess calcium
in all species may cause hypercalcitonism with decreased osteoclastic activity and skeletal remodeling. In dogs, disorders of enchondral ossification with curved radius and osteochondrosis have been demonstrated; secondary iron deficiency anemia occurs in piglets.
calcium fluoride
naturally occurring mineral. Called also fluorspar, fluorite.
calcium gel
contains high levels of calcium; given to cows as a drench or in the feed as a prophylaxis against milk fever.
calcium gluconate
a calcium replenisher and antidote to fluoride or oxalate poisoning.
calcium gout
see calcinosis circumscripta.
calcium homeostasis
maintenance of normal calcium metabolism by the combined effects of adequate alimentary intake, renal excretion, parathyroid hormone involvement, 1,25 dihydroxycholecalciferol (or calcitriol) and calcitonin, plasma protein binding and deposition in tissues.
calcium hydroxide
an astringent compound used topically in solution or lotions; in dentistry used to encourage deposition of secondary dentine. Called also slaked lime. In solution, called lime water.
idiopathic calcium phosphate deposition
thought to be inherited as an autosomal dominant trait in Great Danes commencing in puppies about 5 weeks old, characterized by incoordination with deformity and displacement of the 7th cervical vertebra and mineral deposits in the intervertebral joints, in serous and synovial membranes and mineralization in most other tissues.
calcium lactate
used for supplementing the diet with calcium; contains 18% calcium. As calcium sodium lactate, containing 8% calcium, it is more soluble and can be used in drinking water.
calcium levulinate
a calcium compound used parenterally in the treatment of hypocalcemia; contains 14.8% calcium.
calcium mandelate
administered orally and used as a urinary antiseptic.
calcium nitrate
used as an additive during cheese making to control fermentation. Whey from this cheese may cause nitrate poisoning in pigs.
nondiffusible calcium
protein-bound fractions of plasma calcium.
calcium nutritional deficiency
nutritional deficiency of calcium is rarely primary except in carnivores on an all-meat diet. Secondary deficiency is usually the result of diets having too high a content of phosphorus. The outcome of either deficiency may be nutritional hyperparathyroidism, rickets, osteomalacia, osteodystrophy in horse and pigs, and degenerative arthropathy of cattle, depending on the species, age of the animal and availability of vitamin D. Hypocalcemia may not occur because of the activity of parathyroid hormone, but classical tetany and recumbency can occur if the deficiency is prolonged or if they are precipitated by some other factor.
calcium oxalate
a compound occurring in the urine in crystals and in certain calculi. See also oxalate urolith.
calcium oxide
alkaline and capable of causing gastroenteritis. There is a high concentration in basic slag and this may contribute to that poisoning.
calcium pantothenate
a calcium salt of the dextrorotatory isomer of pantothenic acid; used as a growth-promoting vitamin.
calcium phosphate
one of three salts containing calcium and the phosphate radical: dibasic and tribasic calcium phosphate are used as sources of calcium; monobasic calcium phosphate is used in fertilizer and as a calcium and phosphorus supplement. An important constituent of uroliths.
calcium : phosphorus ratio
the ratio of calcium to phosphorus in the diet, 1 : 1 to 1 : 2 is usually considered to be adequate for proper calcium nutritional status in most animal species. Diets outside this range are likely to cause osteodystrophies. Animals grazing phosphorus-deficient pasture, and those being intensively fed on grain rations which have an abnormally high phosphorus content, are the principal subjects. Horses on heavy grain diets and dogs and cats on meat diets without calcium supplementation are also targets for the disease.
calcium polycarbophil
a hydrophilic agent used as a bulk laxative in the treatment of constipation and diarrhea.
calcium polysulfide
calcium propionate
protein bound calcium
biologically inert fraction of plasma calcium; most is bound to albumin and globulins with a small fraction complexed to organic and inorganic acids.
calcium silicophosphate
crystals of this mineral are thought to contribute physically to the gastroenteritis caused by basic slag poisoning.
calcium sulfate
the main component of plaster of Paris; also used as a dietary source of calcium and inorganic sulfate sulfur.
calcium sulfide, calcium polysulfide
calcium supplements
include calcium carbonate, gluconate, lactate and phosphate; bone flour, bone meal, ground limestone, chalk.
calcium tungstate screens
cards coated with calcium tungstate crystals are used to sandwich film in a light-tight cassette. They fluoresce when exposed to x-rays and, together with the beam, affect the film emulsion. They reduce the exposure factor required.
urinary calcium