calcium current

calcium current

A term for the flow of Ca2+ through specific channels, which is critical for the release of neurotransmitters from presynaptic vesicles. Voltage-gated calcium channels are divided according to the type of calcium current with which they are associated.

Calcium current types
L—Long-lasting activation.
N—Neural type.
P—Purkinje activation related to the release of neurotransmitters.
R—Poorly understood; found in cerebellar granule cells.
T—Transient activatation.
References in periodicals archive ?
The inhibitory effect of magnolol on the calcium current was expressed as percentage reduction in the steady-state current amplitude with magnolol using the equation: % inhibition = ([I.
2011) proposed that the gravity-directed calcium current is regulated primarily by the activation of mechanosensitive calcium channels at the bottom of the spore, based on data obtained from a silicon microfabricated sensor array.
Using a careful analysis of correlations between the course of alcohol withdrawal seizures and the expression of calcium currents, Georgetown University Medical Center researchers found that the enhancement of total calcium current density in pre-clinical animal studies occur prior to the onset of alcohol withdrawal seizures.
Effects of intracellular free magnesium on calcium current in isolated cardiac myocytes.
Depletion of intracellular calcium stores activates a calcium current in mast cells.
Inhibition of T-type Calcium Current in the Reticular Thalamic Nucleus by a Novel Neuroactive Steroid: Pavle M.
The drug inhibits neuronal calcium currents in vitro, which is hypothesized to play a role in the effectiveness of the drug against neuropathic pain.
A larger SR store will initially lead to an increase in the calcium transient, autoregulation is ensured by (a) more rapid inactivation of subsequent calcium currents and, therefore, (b) reduced calcium entry through L-type calcium channels.
In previous work using individual microsensors, researchers were able to map and measure how calcium currents around the cell correlate with the process of gravity-directed development of the cell.
Now they have worked out that this is because omega-3 essential polyunsaturated fatty acids block excessive sodium and calcium currents in the heart.
They have worked out that this is because omega-3 essential polyunsaturated fatty acids (n-3 PUFAs) specifically block excessive sodium and calcium currents in the heart.
It is not understood how reduced calcium currents are related to some of the symptoms of HypoKPP, such as muscle depolarization and reduced serum potassium.