calcitonin gene-related peptide


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cal·ci·to·nin gene-re·lat·ed pep·tide (CGRP),

a second product transcribed from the calcitonin gene. CGRP is found in nervous and other tissues. It is a vasodilator that may participate in the cutaneous triple response.

cal·ci·to·nin gene-re·lat·ed pep·tide

(CGRP) (kal-si-tō'nin jēn-rĕ-lāt'ĕd pep'tīd)
A second product transcribed from the calcitonin gene. CGRP is found in a number of tissues including nervous tissue. It is a vasodilator that may participate in the cutaneous triple response.
References in periodicals archive ?
Differential calcitonin gene-related peptide (CGRP) and amylin binding sites in nucleus accumbens and lung: potential models for studying CGRP/amylin receptor subtypes.
Calcitonin gene-related peptide in GCF in periodontal health and disease.
Morphine-induced modulation of calcitonin gene-related peptide levels.
An antibody that blocks the calcitonin gene-related peptide (CGRP) pathway to prevent migraine headaches
Swindon Zydis Limited, a subsidiary of Catalent (CTLT) to provide Catalent's Zydis ODT fast-dissolving formulation for the development of Biohaven's lead calcitonin gene-related peptide, or CGRP, receptor antagonist product candidate, rimegepant.
It functions by targeting and inhibiting the Calcitonin Gene-Related Peptide (CGRP) receptor, which is considered to play a key role in activation of migraine.
Galcanezumab is a once-monthly, subcutaneously injected calcitonin gene-related peptide (CGRP) antibody under evaluation for the prevention of episodic and chronic migraine and cluster headache.
Calcitonin gene-related peptide expression in sepsis: postulation of microbial infection-specific response elements within the calcitonin I gene promoter.
Calcitonin Gene-Related Peptide and Substance P (Ranjinidevi Ambalavanar and Dean Dessem).
Galcanezumab is a monoclonal antibody specifically designed to bind to and inhibit the activity of calcitonin gene-related peptide, which is believed to play a role in migraine and cluster headache.
According to the company, rimegepant is a second-generation, small molecule, calcitonin gene-related peptide (CGRP) receptor antagonist being developed for the acute treatment of migraine.
If approved, Aimovig is expected to be the first-and-only monoclonal antibody targeting the calcitonin gene-related peptide (CGRP) receptor, specifically designed for the prevention of migraine.

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