calcifediol


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calcifediol

 [kal″sĭ-fĕ-di´ol]
25-hydroxycholecalciferol (a form of vitamin D), used in the treatment of hypocalcemia, hypophosphatemia, rickets, and osteodystrophy associated with various medical conditions including chronic renal failure and hypoparathyroidism, administered orally.

cal·ci·di·ol

(kal-sĭ-dī'ol),
First step in the biologic conversion of vitamin D3 to the more active form, calcitriol; it is more potent than vitamin D3.

calcifediol

/cal·cif·e·di·ol/ (kal″sif-ĕ-di´ol) see 25-hydroxycholecalciferol.

calcifediol

[kal′sifē′dē·ol]
a major transport form of vitamin D.
indication It is prescribed in the treatment of metabolic bone disease associated with chronic renal failure.
contraindications Hypercalcemia, vitamin D toxicity, malabsorption syndrome, decreased renal function, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse effects are renal toxicity and those reactions associated with hypercalcemia, such as soft tissue calcification and GI and central nervous system disturbances.

calcifediol

nonproprietary name for 25-hydroxycholecalciferol, used as a calcium regulator in the treatment and management of metabolic bone disease or hypocalcemia associated with chronic renal failure.
References in periodicals archive ?
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The goal for the treatment group was to achieve serum calcifediol levels between 32 and 48 ng/mL for 20 weeks.
Researchers hypothesized that vitamin D supplementation would reduce the degree of chronic pain experienced by FMS patients with low levels of calcifediol and also might improve other symptoms.
Low blood levels of calcifediol are especially common in patients with severe pain and fibromyalgia.
We therefore set out to determine whether raising the calcifediol levels in these patients would alleviate pain and cause a general improvement in concomitant disorders," the researcher said.
The study Calcifediol (CAS 19356-17-3) Market Research Report 2010 presents an overview of the Calcifediol market globally and regionally by contemplating and analyzing its parameters.
examines applications of Calcifediol, its consumers
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Repeated administration of these therapies induces CYP24, and consequently depletes blood levels of calcifediol, a condition known as vitamin D insufficiency.