000 IU per week intramuscularly for 3 weeks, 1 gg alpha calcidiol
and 1000 mg elemental calcium plus 880 IU vitamin D3 per day orally.
Both forms are converted in the liver to the body's main storage form of vitamin D, known as calcidiol
, and then in the kidneys to the physiologically active form, or calcitriol.
Vitamin D3 is made in the skin when 7-dehydrocholesterol reacts with ultraviolet-B (UVB) rays from sunlight at wavelengths between 270-300 nm and is stored in the blood as calcidiol
Rational and results of weekly treatment with calcidiol
in postmenopausal and senile osteoporosis.
Low serum calcidiol
concentration in older adults and reduced muscular function.
It is now generally accepted that most people are deficient in vitamin D, which is carried in the bloodstream to the liver and converted into the prohormone, calcidiol
In Stages 3 to 5 CKD (not receiving dialysis), levels of calcidiol
(native vitamin D) are often decreased.
The best way to measure how much vitamin D a person has stored is to measure the amount of a substance called calcidiol
in his or her blood.
He is the original discoverer of the biologically active metabolites of vitamin D, and discovered and synthesized calcidiol
The first occurs in the liver and converts vitamin D to 25-hydroxyvitamin D [25(OH) D], also known as calcidiol
From here, vitamin D3 is transported to your liver, where it is combined with the 25-hydroxylase enzyme to form calcidiol
(25-hydroxycholecalciferol or 25-hydroxyvitamin D).
, season, and serum parathyroid hormone concentrations in healthy elderly men and women.