calbindin-D9k

calbindin-D9k

A calcium-binding protein encoded by S100G, which is found in the intestinal epithelial cells. It has two EF-hand-type calcium-binding domains along its single 263-residue chain. It mediates calcium transport across the intestine from the apical side, which is regulated by TRPV6, a calcium channel to the basal pole of the enterocyte, where PMCA1 uses ATP to pump calcium into the circulation.
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The burst of calcium release from the ER of muscle cells is buffered by the presence of calcium-binding proteins such as calbindin-D9k and parvalbumin.
Downregulation of PCNA and calbindin-D9k protein levels after BPA exposure were confirmed by Western blot analysis (see Supplemental Material, Figure S1B,C).
Calbindin-D9k (CaBP9k) localization and levels of expression in trophoblast cells from human term placenta.
Calbindin-D9K gene expression in rat chorioallantoic placenta is not regulated by 1,25-dihydroxyvitamin D3.
Tetrabromodiphenyl other (BDE-47) evokes estrogenicity and calbindin-D9k expression through an estrogen receptor-mediated pathway in the uterus of immature rats.
Studies in rats have shown that subcutaneous injection of p-NP in late pregnancy induces calbindin-D9k (CaBP-9k) mRNA and protein expression in maternal and neonatal uteri, suggesting its potential transfer through the placenta (Hong et al.
Biology and physiology of calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors.
Conflict of estrogenic activity by various phthalates between in vitro and in vivo models related to the expression of Calbindin-D9k.
Examples of differentially expressed representative genes include calbindin-D9k (vitamin D-dependent calcium-binding protein), oxytocin, adipocyte complement related protein (30 kDa), lactate dehydrogenase A, and calcium-binding protein A6 (calcyclin).
Calbindin-D9k mRNA is tightly regulated during the estrous cycle in the rat uterus.
17 Beta-estradiol stimulates the calbindin-D9k (CaBP9k) gene expression at the transcriptional and posttranscriptional levels in the rat uterus.