calbindin-D28k

calbindin-D28k

A calcium-binding protein encoded by CALB1, which is found in the kidney and neuroendocrine cells of the cerebellum and elsewhere. It has four EF-hand-type calcium-binding domains along its single 263-residue chain. It mediates calcium absorption which, in the brain, occurs independent of vitamin D.
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Relationship between calbindin-D28K in the A and B cells of rat endocrine pancreas and secretion of insulin and glucagon: Influence of vitamin D3deficiency and 1, 25 dihydroxyvitamin [D.
Gene cloning, sequencing and eukaryotic expression plasmid construction of chicken calbindin-D28k Chin J Anim Vet Sci 2008;39:1329-35.
2]D3 is believed to be vital for insulin exocytosis by increasing the expression of calbindin-D28K in [beta]-cells.
Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease.
Blatt, "Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k," Cerebellum, vol.
Expression of calbindin-D28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid beta-peptide.
Cyclosporine A-induced hypercalciuria in calbindin-D28k knockout and wild-type mice.
Prevention of glucocorticoid-induced apoptosis in osteocytes and osteoblasts by calbindin-D28k.
Phytoestrogens alter hypothalamic calbindin-D28k levels during prenatal development.
Differential localization of class III, beta-tubulin isotype and calbindin-D28k defines distinct neuronal types in the developing human cerebellar cortex.
Types of neurons, synaptic connections and chemical characteristics of cells immunoreactive for calbindin-D28k, parvalbumin and calretinin in the neocortex.