calbindin-D28k

calbindin-D28k

A calcium-binding protein encoded by CALB1, which is found in the kidney and neuroendocrine cells of the cerebellum and elsewhere. It has four EF-hand-type calcium-binding domains along its single 263-residue chain. It mediates calcium absorption which, in the brain, occurs independent of vitamin D.
Mentioned in ?
References in periodicals archive ?
Expression of calbindin-D28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid beta-peptide.
Cyclosporine A-induced hypercalciuria in calbindin-D28k knockout and wild-type mice.
Prevention of glucocorticoid-induced apoptosis in osteocytes and osteoblasts by calbindin-D28k.
Phytoestrogens alter hypothalamic calbindin-D28k levels during prenatal development.
Differential localization of class III, beta-tubulin isotype and calbindin-D28k defines distinct neuronal types in the developing human cerebellar cortex.
Age-related changes in calbindin-D28k, calretinin, and parvalbumin-immunoreactive neurons in the human cerebral cortex.
Next, intracellular calcium ions are transported by calcium transport proteins, calbindinD9k (S100G) and calbindin-D28k (CALB1), to the b a solateral side of epithelial cells.
Opposing effects of ethanol and nicotine on hippocampal calbindin-D28k expression.