calbindin


Also found in: Acronyms, Wikipedia.

calbindin

One of several vitamin D-induced calcium-binding intestinal proteins, which have an EF hand motif and play a key role in intracellular calcium transport; they are classified based on the number of CA2+-binding EF hand sites.

calbindin

a calcium-binding protein involved in facilitating the absorption of calcium from the intestine and its reabsorption from the glomerular filtrate in the renal tubules and the deposition of calcium in mineralized tissues; two identified forms of the protein are calbindin-D9k and calbindin-D28k.
References in periodicals archive ?
Calbindin is an important transport protein of calcium, as its expression directly affects calcium absorption and metabolism, which in turn regulates bone development [34], The active absorption of calcium in the intestine was also found to be correlated with age [35] and mediated by vitamin D, regardless of gene or non-gene levels [36], Activated vitamin D3 can be combined with its nucleic acid receptor 1,25[(OH).
Calbindin distribution in cortical and subcortical brain structures of normal and rabies-infected mice.
Other proteins such as calretinin, calbindin, and parvalbumin function as localized calcium buffers, especially in the pre- and postsynaptic regions, regulating Ca2+ densities to affect the sensitivity of the neuron to various stresses such as oxidative damage, ischemia, and depolarization.
Immunohistochemical localization of the 1,25(OH)2D3 receptor and calbindin D28k in human and rat pancreas.
subregions of the amygdala), researchers could measure the relative expression of three calcium-binding proteins called parvalbuinin, calretinin, and calbindin.
Cellular distribution of the calcium-binding proteins parvalbumin, calbindin, and calretinin in the neocortex of mammals: phylogenetic and developmental patterns.
Calcium uptake requires epithelial calcium channel TRPV6 and to a lesser extent epithelial calcium channel TRPV5 calbindin D transport calcium across the cell and plasma membrane Ca+channels, prealbumin and NA+, Ca++ exchanger mediate the final delivery of Calcium to the blood stream (12).
Its cytoplasmic concentration is regulated by calcium-binding proteins (CBP), such as paralbumin (PV) and calbindin (CB).
CALCIUM BINDING PROTEIN CALBINDIN D28K WITH ATAXIN-1
In this respect, some evidence indicates that calbindin expression in non pyramidal neurons decreases during the second and third postnatal weeks in parallel with the onset of PV immunoreactivity (Alcantara et al.