calbindin


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calbindin

One of several vitamin D-induced calcium-binding intestinal proteins, which have an EF hand motif and play a key role in intracellular calcium transport; they are classified based on the number of CA2+-binding EF hand sites.

calbindin

a calcium-binding protein involved in facilitating the absorption of calcium from the intestine and its reabsorption from the glomerular filtrate in the renal tubules and the deposition of calcium in mineralized tissues; two identified forms of the protein are calbindin-D9k and calbindin-D28k.
References in periodicals archive ?
Dietary Ca and nPP levels had significant interactions on NaPi-IIb and calbindin mRNA expression levels (p < 0.
subregions of the amygdala), researchers could measure the relative expression of three calcium-binding proteins called parvalbuinin, calretinin, and calbindin.
Calcium transporting protein TRPV6, calbindin D9K and (PMCA lb) are increased by high dietary Ca++ in the duodenum of 1 [alpha] hydrolase null mice, thus demonstrating a 1, 25 [(OH).
Its cytoplasmic concentration is regulated by calcium-binding proteins (CBP), such as paralbumin (PV) and calbindin (CB).
CALCIUM BINDING PROTEIN CALBINDIN D28K WITH ATAXIN-1
Double-labelling for BrdU and other phenotypic markers, revealed that grafted cells had undergone site-specific neuronal differentiation; forming tyrosine hydroxylase-positive neurons in the periglomerular layer of the OB; calbindin-positive neurons in the subgranular and granular layers of the DG; and calbindin and DARPP-32-positive cells in the striatum.
Immunocytochemistry for calbindin to analyze Purkinje cell development, Immuno-cytochemistry of the cultured cells was described previously by Kimura-Kuroda et al.
Our previous studies have shown that calcium binding proteins, especially calbindin D28k (CaB) and parvalbumin have a role in SCA1 pathogenesis.
The HEI-OC1 cells express several molecular markers characteristic of the organ of Corti sensory cells: thyroid hormone, brain-derived neurotrophic factor, calbindin, calmodulin, connexin 26, Math 1, myosin-7a, organ of Corti protein 2, tyrosine kinase receptor B and C, plateler-derived growth factor receptor, and prestin.
Two factors in the transcellular path of absorption that are involved in the uphill transport of calcium can be implicated as part of the discriminatory process, these being the high-affinity calcium-binding protein, calbindin, that presumably serves to increase the intracellular diffusion of calcium, and the plasma membrane ATP-dependent calcium-pump that actively extrudes calcium from the enterocyte [9].