sprue

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sprue

 [sproo]
a chronic form of malabsorption syndrome occurring in both tropical and nontropical forms.
celiac sprue (nontropical sprue) celiac disease.
tropical sprue a chronic disease affecting the digestive system, marked by imperfect absorption of food elements, especially fat, xylose, and vitamin B12, from the small intestine. It is closely related to celiac disease and may be identical to it.



The name sprue derives from a Dutch word describing inflammation of the mouth, which is a frequent symptom. The disease has been recognized for more than 2000 years. It occurs mostly, but not exclusively, in the tropics.
Symptoms and Treatment. Symptoms are loss of appetite, flatulence, anemia, diarrhea, stomach cramps, and extreme loss of weight. Stools are usually pale, greasy, unformed, and foul-smelling, but at times become watery. If a deficiency of vitamin B complex is also present, cracks develop at the corners of the mouth and the tongue becomes smooth, glossy, and bright red.



Treatment consists of a special diet of foods that are low in fat and high in protein. Diets free of gluten, a viscid grain protein, may be prescribed. Liver preparations, folic acid, calcium lactate tablets, vitamin B12, and iron supplements to provide food elements that are not absorbed, as well as skim milk and ripe bananas, have produced favorable results. Antibiotics have proved temporarily successful, but their prolonged use is not recommended.

Cases of sprue that are recognized early respond better to treatment than do cases of long standing. Appetite and weight return rapidly. The time required for complete recovery is prolonged, however, especially in extreme cases.

sprue

(sprū),
1. Primary intestinal malabsorption with steatorrhea. Synonym(s): cachexia aphthosa
2. In dentistry, wax or metal used to form the aperture(s) for molten metal to flow into a mold to make a casting; also, the metal that later fills the sprue hole(s).
[D. spruw]

sprue

(sproo)
1. a chronic form of malabsorption syndrome, occurring in both tropical and nontropical forms.
2. in dentistry, the hole through which metal or other material is poured or forced into a mold.

celiac sprue  see under disease.
collagenous sprue  an often fatal condition resembling celiac sprue but unresponsive to withdrawal of dietary gluten, characterized by extensive deposition of collagen in the lamina propria of the colon.
nontropical sprue  celiac disease.
refractory sprue 
1. malabsorption and flat jejunal mucosa unresponsive to withdrawal of dietary gluten.
2. celiac disease in which initial responsiveness to gluten withdrawal deteriorates with time.
tropical sprue  a malabsorption syndrome occurring in the tropics and subtropics, marked by stomatitis, diarrhea, and anemia.
unclassified sprue  refractory s.

sprue

(spro͞o)
n.
A chronic, chiefly tropical disease characterized by diarrhea, emaciation, and anemia, caused by defective absorption of nutrients from the intestinal tract.

sprue

[spro̅o̅]
Etymology: D, sprouw, kind of tumor
a chronic degenerative disorder resulting from malabsorption of nutrients from the small intestine and characterized by a broad range of symptoms, including diarrhea; weakness; weight loss; poor appetite; pallor; muscle cramps; bone pain; ulceration of the mucous membrane lining the digestive tract; and a smooth, shiny tongue. It occurs in both tropical and nontropical forms and affects both children and adults. Also called catarrhal dysentery. See also celiac disease, malabsorption syndrome, nontropical sprue, tropical sprue.

sprue

(sprū)
1. Primary intestinal malabsorption with steatorrhea.
2. dentistry Wax or metal used to form the aperture(s) through which molten metal flows into a mold to make a casting; also, the metal that later fills the sprue hole(s).
[D. spruw]

sprue

A disorder in which nutrients are poorly absorbed from the intestine. See also MALABSORPTION.

Sprue

A disorder of impaired absorption of nutrients from the diet by the small intestine (malabsorption), resulting in malnutrition. Two forms of sprue exist: tropical sprue, which occurs mainly in tropical regions; and celiac sprue, which occurs more widely and is due to sensitivity to the wheat protein gluten.

sprue

(sprū)
In dentistry, wax or metal used to form aperture(s) for molten metal to flow into a mold to make a casting; also, metal that later fills sprue hole(s).
[D. spruw]

sprue (sproo),

n in casting the ingate through which molten metal passes into the heated mold. The waste piece of metal cast in the ingate.
sprue base,
n See sprue former and crucible former.
sprue former,
n a cone-shaped base made of metal or plastic to which the sprue is attached. Forms a crucible in the investment material. Also called
crucible former.
sprue pin,

sprue

a chronic form of malabsorption syndrome in humans occurring in two forms, tropical, which is associated with ingestion of gluten-containing foods (called also celiac disease), and nontropical. Malabsorption syndromes in dogs are sometimes compared with, but are not identical with, sprue.