bystander suppression

bystander suppression

The dampening of immune responses in the immediate vicinity of T cells with TH2 effector functions, which occurs in response to tolerance of oral antigens, mediated by dendritic cells of the gastrointestinal tract.
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Researchers currently believe that COPAXONE(R)-activated T-cells cross the blood-brain barrier, cross-react with myelin antigens and consequently produce bystander suppression of inflammation through the secretion of anti-inflammatory cytokines.
Moreover, a process called bystander suppression causes the cytokines to work on all nearby T1 cells.