butyrylcholinesterase


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BCHE

A gene on chromosome 3q26.1-2 that encodes butyrylcholinesterase, which has a broad substrate spectrum. It contributes to inactivation of the neurotransmitter acetylcholine and can degrade neurotoxic organophosphate esters.
 
Molecular pathology
Mutant alleles at BCHE are responsible for suxamethonium sensitivity.

plas·ma chol·ine·ste·rase

(plaz'mă kō'lin-es'tĕr-ās)
A type of cholinesterase found in plasma.
See also: fluoride number
Synonym(s): butyrylcholinesterase, pseudocholinesterase.

butyrylcholinesterase

the cholinesterase of plasma (a pseudocholinesterase), which is different from the cholinesterase of the myoneural junctions (acetylcholinesterase).
References in periodicals archive ?
25) Therefore, to investigate whether cognitive disorders associated with butyrylcholinesterase as it exists in humans and rats may apply to birds, one aim of this study was to explore a possible association between enzyme concentrations and feather-destructive behavior in psittacine birds.
The area under the ROC curve (AUC) for butyrylcholinesterase activity was 0.
About BNC: Bisnorcymserine (BNC) is a small, orally active compound that selectively inhibits butyrylcholinesterase activity.
Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
What is the role of butyrylcholinesterase in the pharmacokinetics of succinylcholine?
The following values were evaluated: WBC counts, RBC counts, PCV, hemoglobin, heterophils, lymphocytes, monocytes, eosinophils, prealbumin, albumin, [alpha]-globulin, [beta]-globulin, [gamma]-globulin, total protein, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase, creatine kinase, calcium, phosphorus, iron, cholesterol, glucose, triglycerides, uric acid, urea, creatinine, total solids, bile acids, and butyrylcholinesterase.
The compound targets AD via selective butyrylcholinesterase inhibition (BChEI) as well as with a disease modifying activity via amyloid precursor protein (APP) inhibition.
Amaryllidaceae alkaloid properties include being antitumor, antibacterial, antifungal, antimalarial, antiviral, analgesic and acetylcholinesterase and butyrylcholinesterase inhibitory (Kulhankova et al.
Trichloroethylene: Further studies of the effects on body and organ weights and plasma butyrylcholinesterase activity in mice.
technology platform in the production of PharmAthene's next generation recombinant butyrylcholinesterase (rBChE) bioscavenger.
Because of our interest in butyrylcholinesterase as a marker of metabolic syndrome (30), we also included the results of this measurement in the data analysis.
At the same time we are progressing Bisnorcymserine (BNC), a centrally active, reversible butyrylcholinesterase inhibitor, into its first clinical safety trial.