buserelin


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buserelin

A long-acting GnRH-gonadotropin-releasing hormone analogue, which causes permanent pitutary stimulation and downregulates the pituitary-gonadal axis, blocking testosterone production in the testes; it has been used to treat metastatic prostate and breast cancer, to create pseudomenopause to reduce the size and number of endometriotic lesions and fibroids. It has also been used for hirsutism, to induced ovulation and for in vitro fertilisation.

buserelin

Suprefact® Infertility A long-acting gonadotropin-releasing hormone analogue which downregulates the pituitary-gonadal axis, block testosterone production in the testes; it has been used to treat metastatic prostate CA. See Disease flare.

buserelin

A gonadothropin-releasing hormone drug used in the treatment of ENDOMETRIOSIS and INFERTILITY. Brand names are Suprecur and Suprefact.
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Most men received goserelin acetate (56%), with the remaining patients being treated with leuprolide acetate (32%), buserelin acetate (5%); 3 patients (7%) had several different GNRH agonists or antagonists prescribed over time.
Studies have also evaluated the use of other GnRH agonists, such as buserelin, in a laboratory setting in order to evaluate testosterone secretory capacity in the initial hyperstimulatory stage.
The buserelin stimulation test was performed for evaluating the hypothalamus-pituitary-gonadal axis as described previously (20).
Miscarriage rates following in-vitro fertilisation are increased in women with polycystic ovaries and reduced by pituitary desensitisation with buserelin.
04 g body weight (BW)) were injected with aELH and GnRHs, including buserelin (mammalian GnRH analogue), octopus GnRH (octGnRH), and tunicate GnRH-I (tGnRH-I), at doses of 20 ng/g BW and 200 ng/g BW.
LH and FSH response of Holstein heifers to fertirelin acetate, gonadorelin and buserelin.
Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo, Pharm.
Treatment with buserelin acetate and flutamide, standard hormone therapy for the treatment of prostate cancer, started on day 1 and continued throughout the study.
A few drugs can cause flushing - tamoxifen, glyceryl trinitrate, isosorbide dinitrate, buserelin, goserelin, leuprorelin and triporelin.
Report findings also reveal that a gradual increase and continued use of branded luteinizing hormone-releasing hormone (LHRH) agonists, such as AstraZeneca's Zoladex and Pharm-Sintez's Buserelin, will supplement prostate cancer market growth in Russia through 2016.
T levels >20 ng/dL were found in 17% (7/41), 19% (4/21) and 28% (2/7) of patients on goserelin, leuprolide and buserelin, respectively.