burst-forming unit

burst-forming unit

A small, partially differentiated lymphocyte-like progenitor cell which arises from a pluripotent stem cell, the colony-forming unit for granulocytes(CFU-GEMM), RBCs, megakaryocytes and monocytes in the bone marrow, giving rise to either RBCs (BFU-E) or megakaryocytes (BFU-Meg); these in turn give rise to colony-forming units. The so-called bipolar BFUs have either erythroid or megakaryocytic differentiation.


, burst-forming unit,


A stem cell that produces red blood cell progeny and not blood cells of other lineages.
References in periodicals archive ?
Colony-forming unit granulocytemacrophage (CFU-GM), colony-forming unit erythroid (CFU-E), burst-forming unit erythroid (BFU-E), and colonyforming unit mix (CFU-Mix) were counted on days 5, 7, 9, and 12, respectively, using a microscope according to the manufacturer's protocol.
Results of colony-forming unit erythroid (CFU-E), granulocyte-macrophage (CFU-GM), burst-forming unit erythroid (BFU-E), and colony-forming unit mix (CFU-Mix) assays of bone marrow of iron overload (Fe) mice and after the administration of deferasirox (DFX) or N-acetyl-L-cysteine (NAC).