buprenorphine


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buprenorphine

 [bu″prĕ-nor´fēn]
a synthetic opioid agonist-antagonist derived from thebaine, used in the form of the hydrochloride salt as an analgesic for moderate to severe pain and as an anesthesia adjunct. Administered sublingually or by intramuscular or intravenous injection.

buprenorphine

/bu·pre·nor·phine/ (bu″prĕ-nor´fēn) a synthetic opioid agonist-antagonist derived from thebaine, used as the hydrochloride salt as an analgesic and as an anesthesia adjunct.

buprenorphine

(byo͞o′prə-nôr′fēn′)
n.
A semisynthetic opioid drug, C29H41NO4, used usually in its hydrochloride form as an analgesic and, in combination with naloxone, for long-term treatment of addiction to opioids such as heroin.

buprenorphine

[bu′prĕ-nor′fēn]
a synthetic opioid agonist-antagonist derived from thebaine, used in the form of the hydrochloride salt as an analgesic for moderate to severe pain and as an anesthesia adjunct. Administered sublingually or by intramuscular or IV injection.
indications It is administered parenterally for the relief of moderate to severe pain and is used in tablet form to treat opioid dependence.
contraindication This Schedule V controlled substance is contraindicated for patients who may be opioid dependent.
adverse effects Among the reported adverse effects are respiratory depression, sedation, nausea, dizziness, vertigo, headache, vomiting, miosis, diaphoresis, and hypotension.

buprenorphine

A formulation of semi-synthetic opioid which may be superior to methadone in reducing heroin and cocaine abuse/dependence.

Adverse effects
Sedation, constipation.

buprenorphine

Addiction medicine An agent that may be superior to methadone in ↓ heroin and cocaine abuse Side effects Sedation, constipation. Cf Methadone.

buprenorphine

A powerful painkilling drug that binds to the body's opioid receptors. It acts for 6–8 hours. Brand names are Subutex, Temgesic and Transtec.

buprenorphine

an analgesic and opiate antagonist. Its analgesic effects are much greater and last much longer than those of morphine.
References in periodicals archive ?
Sublocade is the first and only therapy that, at steady state, delivers buprenorphine at a sustained rate of at least 2 ng/mL over a 1-month period," Shaun Thaxter, chief executive officer of the drug's manufacturer, Indivior, said in a press release.
In the clinical trials, the overall safety profile for SUBLOCADE, given by a healthcare provider, was consistent with the known safety profile of transmucosal buprenorphine, concluded the company.
A total 81% of infants in the methadone group developed NAS, compared with 50% of the buprenorphine group.
FDA has granted Fast Track and Priority Review designations for CAM2038 buprenorphine weekly and monthly depot for the treatment of opioid use disorder and will convene an Advisory Committee meeting for CAM2038 in Q4 2017.
Clonidine is not as effective as buprenorphine for detoxification, but it may be used when buprenorphine is contraindicated.
This study now provides high-quality evidence to allow such groups to consider buprenorphine as a viable tool when a drug is needed for more severe neonatal abstinence syndrome," added Dr.
Buprenorphine is a p-agonist opioid drug, but also [kappa]-opioid receptor antagonist in most species, that is efficacious for treating moderate pain in small animals.
Right now, monthly patient censuses indicate that there are about 3234 buprenorphine prescribers providing care for 245,016 opioid-dependent patients, and fewer than 20% of those prescribers are FPs.
Notes from the field: emergency department visits and hospitalizations for buprenorphine ingestion by children-United States, 2010-2011.
An implantable buprenorphine delivery system reduces adherence issues and may improve efficacy," wrote Richard N.
Buprenorphine is a partial opioid agonist that blocks the effects of full agonists and dulls withdrawal symptoms.