brush biopsy


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

biopsy

 [bi´op-se]
removal and examination, usually microscopic, of tissue from the living body, often to determine whether a tumor is malignant or benign; biopsies are also done for diagnosis of disease processes such as infections.
Technique for endometrial biopsy. Longitudinal strips of the endometrium are sampled using an in-and-out and rotational motion. From Rakel, 2000.
aspiration biopsy one in which tissue is obtained by application of suction through a needle attached to a syringe.
brush biopsy one in which the sample is obtained by a brush with stiff bristles introduced through an endoscope, such as for a tissue sample from an inaccessible place such as the renal pelvis or bronchus.
chorionic villus biopsy chorionic villus sampling.
cone biopsy one in which an inverted cone of tissue is excised, as from the uterine cervix.
endoscopic biopsy removal of tissue by instruments inserted through an endoscope.
excisional biopsy removal of biopsy tissue by surgical cutting, such as a lumpectomy.
fine-needle aspiration biopsy aspiration biopsy using a fine needle. For superficial tissue such as the thyroid, breast, or prostate the needle is unguided, but for deep tissue it must be guided radiologically.
incisional biopsy biopsy of a selected portion of a lesion.
needle biopsy (percutaneous biopsy) one in which tissue is obtained by insertion through the skin of a special type of needle (see biopsy needle).
punch biopsy one in which tissue is obtained by a punch-type instrument.
sentinel node biopsy biopsy of a sentinel node (the first lymph node to receive lymphatic drainage from a malignant tumor). It is identified as follows: a dye and a radioactive substance are injected into the body, which causes certain nodes to “light up” like a sentinel, indicating that they are the most appropriate ones for examination. They are detected by both the light created by the dye and the radioactive substance that is monitored by a gamma camera. If the sentinel nodes do not contain malignant cells, this usually eliminates the need for removal of more distal nodes. Called also intraoperative lymphatic mapping.
shave biopsy biopsy of a skin lesion by excising it with a cut parallel to the surface of the surrounding skin.
stereotactic biopsy biopsy of the brain using a stereotactic technique to locate the biopsy site. This can be done as a minimally invasive surgery technique. The patient's head is held in a special rigid frame so that a probe can be directed into the brain through a small hole in the skull.
sternal biopsy biopsy of bone marrow of the sternum removed by puncture or trephining; see also sternal puncture.

brush biopsy

biopsy obtained by abrading the surface of a lesion with a brush to obtain cells and tissue for microscopic examination.

brush biopsy

the use of a catheter with bristles that is inserted into the body to collect cells from tissues.

bronchial brushing

A procedure in which cells from the mucosa of the upper airways—trachea, bronchi, bronchioles—are obtained for cytologic evaluation under direct bronchoscopic visualisation of suspicious mucosal lesions. Bronchial brushing specimens are used to establish a diagnosis of malignancy and have a high degree of accuracy, comparing favourably with the biopsy in confirming the presence of malignancy; if used with a protected brush catheter, the relatively uncontaminated material can be cultured for various organisms.

brush bi·op·sy

(brŭsh bī'op-sē)
Obtained by abrading the surface of a lesion with a brush to obtain cells and tissue for microscopic examination.

brush bi·op·sy

(brŭsh bī'op-sē)
Use of a stiff brush to abrade surface cells of a lesion for automated microscopic analysis; generally used in screening for oral cancer.

biopsy

removal and examination, usually microscopic, of tissue from the living body. Biopsies are usually done to determine whether a tumor is malignant or benign; however, a biopsy may be a useful diagnostic aid in other disease processes such as infections.

aspiration biopsy
biopsy in which tissue is obtained by application of suction through a needle attached to a syringe.
bite biopsy
instrumental removal of a fragment of tissue.
bone marrow biopsy
obtaining a sample of bone marrow, usually by needle aspiration, from a long bone, rib or sternum, for cytological examination.
Enlarge picture
Needle aspiration of bone marrow. By permission from Ettinger SJ, Feldman E, Textbook of Veterinary Internal Medicine, Saunders, 2004
brush biopsy
removal of cells and tissue fragments using a brush with stiff bristles (introduced through an endoscope). Effective in obtaining tissue samples from inaccessible places such as the renal pelvis.
closed biopsy
one carried out without access through an open incision such as a laparotomy. An example is a percutaneous, fine needle aspirate.
cone biopsy
biopsy in which an inverted cone of tissue is excised, as from the uterine cervix.
cytological biopsy
obtaining specimens of cells by various methods including irrigation of a hollow tube.
biopsy dart
an alternative to immobilization of large and wild animals; a dart which cuts a skin bipsy, then falls out. Limited to use for superficial lesions.
endoscopic biopsy
removal of tissue by appropriate instruments through an endoscope.
excisional biopsy
biopsy of tissue removed from the body by surgical cutting.
exploratory biopsy
a combination of exploratory surgery to determine size and location of a lesion and the taking of a biopsy.
fine needle biopsy
see needle biopsy (below).
hepatic biopsy
may be by transperitoneal incision, more commonly by percutaneous needle or trocar and cannula technique.
incisional biopsy
biopsy of a selected portion of a lesion.
needle biopsy
biopsy in which tissue is obtained by puncture of a tumor, the tissue within the lumen of the needle being detached by rotation, and the needle withdrawn.
punch biopsy
see punch biopsy.
Robson-Heggers biopsy
a procedure for the collection of a piece of tissue from an infected wound in order to determine the extent and the nature of the infection.
sternal biopsy
biopsy of bone marrow of the sternum removed by puncture or trephining (see also sternal puncture).
surface biopsy
sample of cells scraped from the surface of a lesion or obtained by impression smears.
surgical biopsy
one obtained during a surgical procedure.
synovial biopsy
by a needle biopsy technique or through an arthrotomy incision using special forceps for a bite biopsy.
total biopsy
obtained by removal of the entire lesion. May be for therapeutic as well as diagnostic purposes.
ultrasound-guided biopsy
use of ultrasonography to guide the passage of a needle or biopsy instrument into an internal organ or lesion.
References in periodicals archive ?
The brush biopsy is based on the technology used in the Star Wars anti-missile system.
David Perry, President of Millennium Medical Devices, commented, "The OralCDx brush biopsy is very accurate and has been the subject of well controlled, randomized, clinical trials.
We also encourage more dentists to adopt use of the brush biopsy when they see a small red or white spot.
The fact that the brush biopsy with computer-assisted tissue analysis was found to increase detection by over 40 percent in even these highly experienced esophageal GI specialty centers demonstrates the potential of this technique," said Sharmila Anandasabapathy, MD, chief of Endoscopy, The Mount Sinai Medical Center in New York and lead author of the academic center study.
The OralCDx brush biopsy is a remarkably simple, painless procedure that has the potential to reduce oral cancer mortalities in our country," says Oral Health America President and CEO Robert Klaus.
While our benefit programs have always covered traditional scalpel biopsies, and continue to do so, the brush biopsy represents a breakthrough in the fight against oral cancer," said Dr.
OralCDx is a computer-assisted brush biopsy test that can determine if oral lesions contain potentially dangerous precancerous or cancerous cells.
four cleanings per year - two routine and two periodontal; -- tooth-colored fillings for posterior teeth; and -- brush biopsy procedures.
Two non-invasive procedures have been added to these schedules - brush biopsy (D7288)(3) and a new oral cancer screening procedure (D0431)(3).
Dental professionals play a crucial role in early detection and are adopting a relatively new tool called a brush biopsy to catch oral cancer in its earliest stages or even as a precancerous lesion.
For example, in 2004, Delta Dental's analysis of continuing high levels of oral cancer led to its decision to make coverage of the brush biopsy, a new tool for the early detection and prevention of oral cancer, a standard part of its benefits programs.