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bronchocentric granulomatosis

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bron·cho·cen·tric granulomatosis (brngk-sntrk)
n.
A severe form of allergic bronchopulmonary aspergillosis.

bronchocentric granulomatosis
Chest medicine A condition characterized by a granulomatous replacement of mucosa with eosinophilia and sometimes angiitis, due either to a fungal–allergic bronchopulmonary aspergillosis–or TB reaction or hypersensitivity to various antigens Age grouping Young–± age 22 yrs, typical Sx of asthma and eosinophilia; older group with neither Clinical Progressive dyspnea, cough, hemoptysis, malaise, fever; cavities may result from lung abscesses, cavitated granulomas, distended bronchi; 75% of BGs are unilateral, and more common in upper lobes Imaging Lobar and segmental consolidation and atelectasis, irregular masses, linear opacities, shadows due to abnormal bronchi, mucoid impaction. See Allergic bronchopulmonary aspergillosis.


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Eosinophilic lung diseases Allergic syndromes Allergic bronchopulmonary aspergillosis Allergic bronchopulmonary syndromes associated with fungi Bronchocentric granulomatosis Associated with parasitic infestation Tropical eosinophilia (filariasis) Ascaris spp.
Bronchocentric granulomatosis (BCG), first described by Liebow in 1973,[1] consists of filling of the lumen of a bronchiole with dense plugs of mucus and cellular debris, necrosis of mucosa, and its replacement by polymorphous inflammation and radially palisaded epithelioid histiocytes.
Our patient also appears to have had bronchocentric granulomatosis by pathology.
 
 
 
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