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bronchial hyperresponsiveness

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bronchial hyperresponsiveness
Exaggerated bronchial constriction most common in asthma, in response to nonspecific provocation, inhalation of various bronchoconstrictors, but also to physical challenges–eg, exercise, dry or cold air, hypertonic or hypotonic aerosols


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The common denominator underlying the pathogenesis of asthma is bronchial hyperresponsiveness and atopy is the commonest risk factor for asthma development; others are air pollution, respiratory infection, obesity, family size, occupation, as well as tobacco smoking and drugs [1,2].
However, the increased emphasis on asthma as a disease of inflammation leading to bronchial hyperresponsiveness has shifted the use of inhaled aerosol steroids from second-line or third-line therapy to first-line, primary therapy.
1) The characteristic symptomatology is a consequence of this inflammation and the associated bronchial hyperresponsiveness (BHR).
 
 
 
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