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bronchial brushings |
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bronchial brushings Brush biopsy A procedure in which cells from the mucosa of the upper airways–trachea, bronchi, bronchioles are obtained for cytologic evaluation under direct bronchoscopic visualization of suspicious mucosal lesions.
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Cytologic specimens, especially bronchial brushings, yield cohesive groups of cells with hypersecretory features. Seventy subjects, characterized as previously described (13), underwent bronchoscopy, endobronchial biopsy, and bronchial brushings, and provided samples of epithelial cells of greater than 95% purity. 577-586) Pierrou and colleagues report on a study in which they used gene expression profiling to identify genes that are differentially expressed in bronchial epithelial cells obtained by bronchial brushings from well-characterized healthy nonsmoking and smoking subjects, and from current smokers with COPD (8). |
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