bromelains


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bromelains

a group of proteolytic and milk-clotting enzymes derived from the pineapple plant, Ananas sativus. They are used as anti-inflammatory agents.
References in periodicals archive ?
In order to evaluate the effect of spray drying process parameters that enhance the quality of powdered bromelain and its activity, a randomized 23 full factorial design (two-level and three-factor with three center points) was devised.
Statistical software (MINITAB release 14) was employed for the designing and analysis of the experimental data so as to measure the effects of those operating variables on bromelain activity.
In order to investigate and assess the model and the best operating conditions for the bromelain spray drying, the combination of the coefficient of determination ([R.
The experimental run which exhibited highest bromelain activity was subjected to analysis for determination of moisture content, residual protein content and product recovery yield.
In a recent blinded study from Germany, researchers divided 90 patients with painful osteoarthritis of the hip into two groups: one half receiving an oral enzyme preparation containing bromelain for six weeks, while the other half received the anti-inflammatory drug diclofenac (sold under the brand name Voltaren[R] and generic names).
Another study comparing a standardized commercial enzyme preparation containing bromelain with diclofenac reached the same conclusion.
Pain evaluation was based on patient symptom scores, which were reduced by 41% in the 200 mg bromelain group and by 59% in those receiving 400 mg of bromelain, indicating a dose- response relationship.
Together, these findings reveal that bromelain may provide safe, effective relief from acute and chronic joint pain caused by arthritis and other conditions.
The study reported here was aimed at investigating, in an open manner, the effect of daily bromelain supplementation for 30 days at two doses on acute mild knee pain in otherwise healthy adults.
Initially, a general questionnaire was used to screen volunteers, and those suitable for study were randomly assigned equally and by accession into the study to receive either 200 or 400 mg (ie 1 or 2 tablets per day) of bromelain (Bromelin[TM], Lichtwer Pharma (UK) Ltd.
The overall PGWB scores were significantly increased after treatment with both 200 mg and 400 mg per day bromelain (P = 0.
Bromelain has been the subject of scientific research since it became commercially available over 50 years ago (Taussig and Batkin, 1988).