brofaromine


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brofaromine

A reversible monoamine oxidase inhibitor (MAOI) with serotonin reuptake-inhibiting activity, which is used to manage depression and anxiety.

Pros
In contrast to other MAOIs, it does not cause hypertension, encephalopathy, hepatotoxicity or hyperthermia.
References in periodicals archive ?
record_id=11955) of randomized, controlled trials of medications for PTSD concluded that no drugs have adequate data showing efficacy, including SSRIs, the [alpha]-adrenergic blocker prazosin, anticonvulsants, the atypical antipsychotics olanzapine (Zyprexa) and risperidone (Risperdal), benzodiazepines, the MAO inhibitors phenelzine and brofaromine (Consonar), other antidepressants, and drugs such as naltrexone or inositol.
57) Of these agents, tranylcypromine is the most likely to raise blood pressure, as opposed to moclobemide and brofaromine, which are the least likely to elevate pressures.
Brofaromine versus lithium addition to maportiline: A double-blind study in maprotiline refractory depressed outclients.
perforatum extract Some antidepressants such as inhibits the activity of moclobemide, cimoxatone and monoaminoxidase enzymes, types brofaromine are monoaminoxidase A and B (Cott, 1997).
For example, moclobemide is a reversible MAOA-specific drug in clinical practice in the UK, whilst brofaromine, cimoxatone, and toloxatone are similar drugs not yet used clinically.
A double-blind comparative study of brofaromine and fluvoxamine in outpatients with panic disorder.
Reversible MAO inhibitors include moclobemide, brofaromine, toloxatone, and befloxatone, all of which are specific for MAO-A.