brittle bone


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to brittle bone: Brittle bone disease

brittle bone

Bone that is abnormally fragile, as in osteogenesis imperfecta.
See also: bone
References in periodicals archive ?
I have told staff at the sorting office that this charge of PS1 is taken from the money sent to Brittle Bone, and this morning the attitude of the young lady who served me seemed to sum up today's society and my impression of the Royal Mail.
Charlotte Proud, from Gateshead, who has osteogenesis imperfecta - commonly known as brittle bone disease
However as this was happening, the bystander was knocked down and received a fractured leg due to his brittle bone condition.
Mereo BioPharma Group plc's (LON: MPH) drug BPS-804 developed for the treatment of osteogenesis imperfecta (OI), otherwise known as brittle bone disease, has been accepted to participate in the European Medicines Agency's (EMA) Adaptive Pathways programme, the company revealed on Monday.
In Manduca's case it is a 45-minute video about brittle bone disease -- osteogenesis imperfecta -- that takes viewers on a tour of her appointments at Children's Hospital in Boston.
They cover the evolution of understanding its clinical and genetic heterogeneity and molecular and biochemical basis; its clinical and genetic classification and epidemiology; research on the condition; bone biology, structure, and biochemistry; its clinical and molecular genetics; key mutations; animal models; brittle bone overlap phenotypes; clinical aspects, including differential diagnosis; organ involvement; orthopedics; physical medicine and rehabilitation; pharmacologic treatment; and the genetic approach to treatment.
Authorities initally said Julie, who was wellknown as a founder member of the national Brittle Bone Society, died from an obstructed airway.
The Brittle Bone Society have helped Emily and her family thanks to donations made by the public to the Pudsey appeal.
The researchers say that the weak tendons and fragile bones characteristic of osteogenesis imperfecta, or brittle bone disease, stem from a genetic mutation that causes the incorrect substitution of a single amino acid in the chain of thousands of amino acids making up a collagen molecule, the basic building block of bone and tendon.
This finding is critical to patients who lack the proper healing process and to individuals prone to broken bones, such as those with osteoporosis and the rare genetic condition known as brittle bone disease," senior author Dr.
Tests will be carried out to see if there is an underlying condition such as brittle bone disease-the most common condition causing child fractures.
Sarah suffers from a rare one-in-a-million brittle bone disease.