bretylium


Also found in: Wikipedia.

bretylium

 [brĕ-til´e-um]
an adrenergic blocking agent used in the form of the tosylate salt to control arrhythmias in certain cases of ventricular tachycardia or fibrillation; administered by intravenous or intramuscular injection.

bre·tyl·i·um

(bre-til'ē-ŭm),
An antiarrhythmic used to treat life-threatening ventricular arrhythmias. Initially releases norepinephrine, then blocks its reuptake, thus depressing excitability of sympathetic nerve terminals.

bretylium

/bre·tyl·i·um/ (brĕ-til´e-um) an adrenergic blocking agent used as the tosylate salt as an antiarrhythmic in certain cases of ventricular tachycardia or fibrillation.

bre·tyl·i·um

(bre-til'ē-ŭm)
An antiarrhythmic used to treat life-threatening ventricular arrhythmias. Initially releases norepinephrine, thenblocks its reuptake, thus depressing excitability of sympathetic nerve terminals.
References in periodicals archive ?
Similarly, the alpha-blocking properties of bretylium might be additive to those of LATUDA, resulting in problematic hypotension.
Other drugs like bretylium or amiodarone may be used; however IV amiodarone has been shown to be as effective as bretylium with added advantage of less hypotension as compared to IV bretylium.
Bretylium (an adrenergic neurone blocking agent used to treat ventricular fibrillation) may facilitate cardioversion.
Voltage gated potassium (Kv) channels in the myocardium are blocked by class III antiarrhythmic drugs like amiodarone and bretylium.
Consider use of fluids and the following drugs during CPCR: atropine, epinephrine, 2 percent lidocaine, naloxone, sodium bicarbonate, and bretylium.
A number of specific therapies have been proposed over the years including bretylium, glucose/insulin/potassium infusions and cardiopulmonary bypass (1-2,5).
drugs, all in prefilled syringes: Dextrose, 50 percent; Sodium Bicarbonate; Bretylium Tosylate; Atropine, Epinephrine 1:10,000; Lidocaine, 2 percent; and Dextrose, 5 percent.
channel blockade (Harrison's modification (6) further divides this class of antiarrhythmics into three subclasses: IA (quinidine and procainamide), IB (lidocaine and phenytoin), and IC (flecainide)); class II, [beta]-adrenergic blockade, propranolol; class III, prolonged repolarization, amiodarone (Cordarone) or bretylium (Bretylol); class IV, [Ca.
Similarly, the alphablocking properties of bretylium might be additive to those of LATUDA, resulting in problematic hypotension.
Intravenous regional anaesthesia block with bretylium had used but was discontinued because of the high incidence of orthostatic hypotension which prevented the discharge of patients from the outpatient clinic.
Due to modest benefits and the invasiveness of the therapies, epidural clonidine injection, intravenous regional sympathetic block with bretylium and spinal cord stimulation should be offered only after careful counseling (B).
8) Class 1A and class III antiarrhythmic agents that may be involved in these events include amiodarone, azimilide, bepridil, bretylium, disopyramide, dofetilide, D-sotalol, flecainide, ibutilide, procainamide, propafenone, quinidine, and tedisamil.