Breast and ovarian cancer susceptibility gene, early onset | definition of breast and ovarian cancer susceptibility gene, early onset by Medical dictionary
BRCA2 (redirected from breast and ovarian cancer susceptibility gene, early onset)
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symbol for a breast cancer gene with activity similar to that of BRCA1.
BRCA2 A gene on chromosome 13q12.3 that encodes a protein which, like BRCA1, is involved in maintenance of genome stability, especially the homologous recombination pathway for double-stranded DNA repair; like BRCA1, it carries a marked increase in the lifetime risk of breast and ovarian cancer.
BRCA2 Molecular oncology A tumor suppressor gene linked to breast and ovarian CA See Tumor suppressor gene.