a glioma, generally an astrocytoma, arising in the medulla, pons, or midbrain.
brainstem gliomaA tumour of the pons and medulla between the aqueduct of Sylvius and the fourth ventricle, which comprises ±2.4% of all intracranial tumours in adults and 15% of pediatric brain tumours, which some authors divide into anatomic regions: tectal, cervicomedullary and diffuse intrinsic pontine, which has a poor prognosis.
Diplopia, facial weakness, headache, nausea, vomiting, dysphagia, gait ataxia, hydrocephalus. Symptoms are linked to the space-occupying nature of these tumours. Death may be caused by increased intracranial pressure and herniation.
Radiation therapy, chemotherapy.
Brainstem gliomas are more indolent in adults than children.
Neurofibromatosis, symptoms of at least 12-month duration before diagnosis, exophytic location, low-grade histology, focal tectal and cervicomedullary tumours, CT calcification.
Younger than 2, multiple brainstem signs, cranial nerve palsies, diffuse pontine lesions of the pons, short duration, high-grade histology.