brain natriuretic peptide

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Related to brain natriuretic peptide: Atrial natriuretic peptide, troponin, C-type natriuretic peptide

brain natriuretic peptide (BNP)

a hormone, originally isolated from porcine brain tissue, having biological effects similar to those of atrial natriuretic peptide and stored mainly in the myocardium of the cardiac ventricles. Blood levels of BNP are elevated in hypervolemic states, such as congestive heart failure and hypertension.

brain natriuretic peptide

An atrial natriuretic peptide-like brain peptide produced predominantly in the cerebral ventricles, which induces diuresis and is secreted in response to fluid overload, as occurs in congestive heart failure.


(pep'tid?) [ pept(ic) + -ide]
A compound containing two or more linked amino acids.

atrial natriuretic peptide

Abbreviation: ANP
Atrial natriuretic factor.

brain natriuretic peptide

B-type natriuretic peptide.

B-type natriuretic peptide

Abbreviation: BNP
A hormone secreted by the left or right ventricle of the heart Concentration of this peptide in the bloodstream rises during episodes of decompensated heart failure.
See: brain natriuretic peptide

cell-penetrating peptide

A peptide that readily crosses cell membranes and therefore can influence cellular functions or carry other molecules that can directly or indirectly perform the same tasks.

endogenous opioid peptide

Any of a group of more than 15 substances present in the brain, certain endocrine glands, and the gastrointestinal tract. They have morphine-like analgesic properties, behavioral effects, and neurotransmitter and neuromodulator functions. Included in this group of chemicals are endorphins, enkephalins, and dynorphin.

glucose-dependent insulinotropic peptide

A hormone released by cells in the upper gastrointestinal tract in response to sugary or fatty meals. It stimulates beta cells in the pancreas to secrete insulin.

immunodominant peptide

Any of the peptides having a strong affinity for binding with class I or II histocompatibility antigens and for stimulating a response by T lymphocytes. Immunodominant peptides are produced by antigen processing, are expressed on the surface of macrophages and other antigen-presenting cells, and may be useful both in desensitizing people to allergens and in vaccine production.
Synonym: immunodominant epitope

natriuretic peptide

Any peptide that stimulates the kidneys to excrete salt and water.

peptide YY

An appetite-regulating protein released by L cells of the mucosa of the gastrointestinal tract in response to a meal. It binds to cells in the arcuate nucleus of the brain, decreases the desire to eat, and creates a feeling of fullness.
References in periodicals archive ?
Brain natriuretic peptide as a novel cardiac hormone in humans: evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide.
Plasma brain natriuretic peptide and the evaluation of volume overload in infants and children with congenital heart disease.
Concentrations of brain natriuretic peptide in the plasma predicts outcomes of treatment of children with decompensated heart failure admitted to the intensive care unit.
Titration of vasodilator therapy in chronic heart failure according to plasma brain natriuretic peptide concentration: randomized comparison of the hemodynamic and neuroendocrine effects of tailored versus empirical therapy.
Brain natriuretic peptide (BNP) and N-Terminal pro brain natriuretic peptide (NT-pro BNP) are useful biochemical markers of left ventricular dysfunction and heart failure.
Jaff will present "Does Elevated Brain Natriuretic Peptide (BNP) Predict Outcomes for Patients With Uncontrolled Hypertension in Renal Artery Stenting?
Multiple factors influence brain natriuretic peptide secretion in heart failure, some of them are renal dysfunction (particularly with estimated glomerular filtration rates <60 ml/min) (42), age and gender (43).
Superiority of brain natriuretic peptide as a hormonal marker of ventricular systolic and diastolic dysfunction and ventricular hypertrophy.
The same was true for plasma brain natriuretic peptide (BNP), a marker of cardiovascular risk; indeed, liraglutide was the sole agent to significantly reduce BNP.
NT-proBNP is a derivative of the hormone brain natriuretic peptide, which is released in response to cardiac stress and has been demonstrated in numerous clinical studies to be an accurate and reliable indicator of cardiac disease risk.